Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 51516-68-8, name is 5-Amino-1-(3-chlorophenyl)-1H-pyrazole-4-carbonitrile, This compound has unique chemical properties. The synthetic route is as follows., Formula: C10H7ClN4
Title compound 2A, 5-amino-1-(3-chloro-phenyl)-1H pyrazole-4-carbonitrile (0.2 g, 0.91 mmol) was suspended in formamide (10 ml). The suspension was heated to 210C for 1 hour then allowed to cool to room temperature. To the reaction mixture was added water (10 ml), the resultant precipitate was collected by filtration, washed with water (2 x 10 ml) and dried on the filter. The crude solid was then purified by column chromatography with ethyl acetate/heptane (1: 1) as the eluent to give the title compound as a white solid (68 mg, 0.278 mmol, 30%). LC-MS: [M+H]+=246, Rt = 1.06 min, 98% purity.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 51516-68-8.
Reference:
Patent; DeveloGen Aktiengesellschaft; Evotec AG; EP1746099; (2007); A1;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics