Synthetic Route of 1280210-79-8, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1280210-79-8, name is tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate, This compound has unique chemical properties. The synthetic route is as follows.
Dissolve 2,6-dihydropyrrolo [3,4-c] pyrazole-5(4H)-tert-butyl carboxylate (12 g, 56.7 mmol) in acetonitrile (100 mL),Add 1-bromo-3- (bromomethyl) -5-methoxybenzene 4b (19 g, 68.1 mmol), Cesium carbonate (64.8 g, 199 mmol), Nitrogen was replaced 3 times, and the reaction was performed in an 80 C oil bath for 3 hours. Filtering the reaction solution,The filtrate was concentrated. The residue was purified by column chromatography (petroleum ether: ethyl acetate = 2: 1) to obtain 2-(3-bromo-5-methoxybenzyl)-2,6-dihydropyrrolo[3,4-c]pyrazole-5(4H)-tert-butyl carboxylate 4c (23 g, yellow oil), yield: 82.9%.
The chemical industry reduces the impact on the environment during synthesis tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate. I believe this compound will play a more active role in future production and life.