Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 30169-25-6, name is 3,6-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazine, A new synthetic method of this compound is introduced below., Product Details of 30169-25-6
3,6-Bis-(3,5-dimethyl-pyrazol-1-yl)-1,2,4,5-tetrazine (1)(4:05 g 15:0 mmol) and 1H-imidazole (2:35 g 35:0 mmol)were suspended in 25 mL acetonitrile and the mixture refluxed for 3 h. After cooling the resulting precipitate was filtered and washed with large amounts of water(1 L), followed by acetonitrile and dichloromethane. 2:69 g (12:6 mmol 84%) of 5 was isolated as an orange powder. – Elemental analysis (C8H6N8, 214.19) exp. (calcd.)in %: C 44.90 (44.86),N 52.03 (52.32), H 2.90 (2.82).- DSC (5 C min1) : Tdec:: 200 C (onset). – 1H NMR([D6]DMSO, 25 C, ppm): d =7.35 (m, 1H, C-H), 8.16 (m,1H, C-H), 8.81 (m, 1H, C-H). – 13C NMR ([D6]DMSO,25 C, ppm): d =117.1 (1C), 121.5 (1C), 132.4 (1C), 153.1(1C). – Raman: n (cm-1)=3158 (10), 3126 (5), 3113 (10),1912 (5), 1537 (7), 1500 (8), 1490 (100), 1407 (13), 1372(2), 1318 (13), 1282 (7), 1254 (2), 1129 (5), 1091 (16), 1048(4), 962 (54), 895 (5), 858 (3), 801 (33), 747 (2), 665 (3), 613 (2). – IR (25 C, ATR): n (cm1)=3155 (w), 3122 (w), 3110(w), 1775 (vw), 1702 (vw), 1648 (vw), 1614 (vw), 1531 (w),1522 (w), 1475 (s), 1366 (w), 1321 (s), 1301 (m), 1260 (m),1233 (w), 1214 (m), 1153 (w), 1104 (m), 1068 (m), 1038(vs), 971 (s), 946 (s), 926 (m), 898 (s), 854 (vs), 762 (vs),693 (w).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.