Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3469-69-0, name is 4-Iodopyrazole, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C3H3IN2
1-Methyl-4-iodopyrazole (18) 4-Iodopyrazole (1) (5.0 g 25.7 mmole) was dissolved in DMF (50 mL), potassium carbonate (4.26 g 30.9 mmole) was added and stirred (2 mins) before iodomethane (1.76 mL, 4.01 g 28.3 mmole) was added. The reaction was stirred rapidly at r.t. for 17 hrs. It was filtered through a Celite pad. The filtrate was evaporated to a small volume, about 10 mL, using a rotary evaporator with a high vac. pump and the water bath at 60 C. Water (120 mL) was added to the residue. The filtered solids on the Celite pad were washed with ethyl acetate (50 ml) and these washings were used to extract the product from the aqueous. The aqueous was extracted with more ethyl acetate (2*50 mL). The combined organics were washed with water (3*30 mL) and with brine; dried and evaporated to give the title compound as a solid 4.56 g, 85%. 1H-NMR (CDCl3, 500 MHz): delta 3.93 (s, 3H) 7.42 (s, 1H), 7.50 (s, 1H).
According to the analysis of related databases, 3469-69-0, the application of this compound in the production field has become more and more popular.