Application of 14531-55-6, The chemical industry reduces the impact on the environment during synthesis 14531-55-6, name is 3,5-Dimethyl-4-nitro-1H-pyrazole, I believe this compound will play a more active role in future production and life.
A mixture of 3,5-dimethyl-4-nitro-1 H-pyrazole (see international patent application WO 2003057673) (3.982g, 28.22 mmol), iodobenzene (11.3 mL, 101.4 mmol), K2CO3 (8.19 g, 59.26 mmol), CuI (268.8 mg, 1.41 mmol), andtrans-N,N?-di-methylcyclohexane-1,2-diamine (890 mL, 5.63 mmol) were heated to 180 C in a microwave reactor for 4h under argon. The reaction mixture was cooled to room temperature, diluted with EtOAc (250 mL), filtered throughcelite, and the product was purified by column chromatography (30?40?75% EtOAc in petroleum ether) to give 4.428g (72%) of the title compound.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,5-Dimethyl-4-nitro-1H-pyrazole, other downstream synthetic routes, hurry up and to see.