Reference of 37687-24-4, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 37687-24-4, name is Diethyl 3,5-pyrazoledicarboxylate, This compound has unique chemical properties. The synthetic route is as follows.
To a solution of 2-bromo-1-(3,4-dihydro-1H-isochromen-/-yl)ethanone (Intermediate 63A, 2.30 g, 8.1 mmol, 90% purity) in acetone (35 ml) were added diethyl 1H-pyrazole-3,5-dicarboxylate (1.56 g, 7.4 mmol) and potassium carbonate (2.75 g, 19.9 mmol). After stirring overnight at room temperature, the solids were filtered off, and the filtrate was concentrated under reduced pressure. The res-idue was purified by flash-chromatography on silica gel (eluent: petroleum ether/ethyl acetate 4:1)to give 2.40 g (83% of theory) of the title compound. LC/MS [Method 23]: Ri = 0.91 min; MS (ESlpos): m/z = 387 [M+H]?.1H-NMR (400 MHz, DMSO-d): 5 [ppm] = 7.84-7.86 (m, 1H), 7.76 (s, 1H), 7.35-7.38 (m, 2H), 6.20 (s, 2H), 4.77 (s, 2H), 4.31 (gq, 2H), 4.20 (q, 2H), 3.92 (t, 2H), 2.89 (t, 2H), 1.31 (t, 3H), 1.17 (t, 3H).
The chemical industry reduces the impact on the environment during synthesis Diethyl 3,5-pyrazoledicarboxylate. I believe this compound will play a more active role in future production and life.