Electric Literature of 60061-68-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 60061-68-9, name is 4-Bromo-3-methyl-5-(trifluoromethyl)-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows.
A solution of 4-bromo-5-dimethyl-3-(trifluoromethyl)-1 H-pyrazole (4.2g, 18.3 mmol) in acetone (5OmL) was treated with K2C03 (5.07g, 36.7mmol) and iodomethane (2.28mL, 36.7mmol) at rt and the reaction mixture was stirred at rt for 16 hr. The reaction mixture was then diluted with ethyl acetate, washed with water and brine, dried over Na2SO4 and evaporated under reduced pressure. The crude product was purified by column chromatography eluting with ethyl acetate/hexane (15:85) to give 4-bromo-1 ,5-dimethyl-3- (trifluoromethyl)-IH-pyrazole (2.7g, 61%). 1H NMR (400 MHz, DMSOd6) oe 3.85 (s, 3H), 2.28 (s, 3H).
The chemical industry reduces the impact on the environment during synthesis 4-Bromo-3-methyl-5-(trifluoromethyl)-1H-pyrazole. I believe this compound will play a more active role in future production and life.