Reference of 37599-58-9, A common heterocyclic compound, 37599-58-9, name is (1H-Pyrazol-3-yl)methanamine, molecular formula is C4H7N3, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: Compound 1 (535 mg, 3.00 mmol, 1 equiv.)was dissolved in MeOH (3 mL). The corresponding amine(3.6 mmol) was added. The reaction mixture was stirred at RT for overnight. The solvent was removed under reduced pressure. The residue was purified by column chromatography(neutral Al2O3, EtOAc/hexane) to give pure compound 2.
The synthetic route of 37599-58-9 has been constantly updated, and we look forward to future research findings.