Related Products of 35277-02-2, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 35277-02-2, name is 4-Fluoro-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows.
A mixture of 4-Chloro-2-methyl-quinolin-8-ol (30 mg, 0.15 mmol) and 4-Fluoro-lH- pyrazole (Shi, Xifeng; Ishihara, Takashi; Yamanaka, Etairoki; Gupton, John T. Tetrahedron Letters 1995, 36, 1527-1530) (33 mg, 0.39 mmol) in NMP (25 muL) was stirred at 150 C for 90 min. The crude product was purified by reversed phase EtaPLC using a gradient of acetonitrile in water with 0.1 % TFA to give the title compound as the TFA salt. MS (m/z): 244.0 [M+H+]
The chemical industry reduces the impact on the environment during synthesis 4-Fluoro-1H-pyrazole. I believe this compound will play a more active role in future production and life.