Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 83-07-8, Name is 4-Aminoantipyrine, molecular formula is C11H13N3O, belongs to pyrazoles-derivatives compound, is a common compound. In a patnet, author is Fang Guannian, once mentioned the new application about 83-07-8, Name: 4-Aminoantipyrine.
Study on the Reaction of Acetone Cyanohydrin with 3,5-Dimethyl-N-alpha,beta-unsaturated Acyl Pyrazole
Cyano compounds are a class of organic compounds with great value. Two different kinds of reactions have been reported using acetone cyanohydrin as reagent and substituted 3,5-dimethyl-N-alpha,beta-unsaturated acyl pyrazole as substrate. The reaction pathway depends on the basic catalysts used when aromatic substituted 3,5-dimethyl-N-alpha,beta-unsaturated acyl pyrazole was used as the substrate. Michael addition reaction occurred in the presence of MgBu 2 with the product yield up to 95%, while alcoholysis reaction of amide occurred in the presence of 1,1,3,3-tetramethvlguanidine (TMG), producing beta-substituted phenyl cyanoacrylates with 84% yield. However, fatty substituted 3,5-dimethyl-N-alpha,beta-unsaturated acyl pyrazole and acetone cyanohydrin underwent Michael addition reaction in the presence of MgBu2 or TMG, the product yield was up to 99%. The possible reaction mechanism when using different basic catalysts was discussed.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 83-07-8. The above is the message from the blog manager. Name: 4-Aminoantipyrine.
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics