Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, Formula: C8H5N3O24233-33-4, Name is 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione, SMILES is O=C1N=NC(=O)N1C1=CC=CC=C1, belongs to pyrazoles-derivatives compound. In a article, author is Fan, Zhenwei, introduce new discover of the category.
Copper-Catalyzed Aerobic Cyclization of ss,gamma-Unsaturated Hydrazones with Concomitant C=C Bond Cleavage
A Cu-catalyzed aerobic oxidative cyclization of ss,gamma-unsaturated hydrazones for the preparation of pyrazole derivatives has been developed. The hydrazonyl radical promoted the cyclization, along with a concomitant C=C bond cleavage of ss,gamma-unsaturated hydrazones. This process has been verified via several control experiments, including a radical-trapping study, an 18O-labeling method, and the identification of the possible byproducts. The advantages of this reaction include operational simplicity, a broad reaction scope, and a mild selective reaction process.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 4233-33-4. Formula: C8H5N3O2.
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics