The important role of 1453-58-3

Synthetic Route of 1453-58-3, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 1453-58-3.

Synthetic Route of 1453-58-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 1453-58-3, Name is 3-Methylpyrazole, SMILES is CC1=NNC=C1, belongs to pyrazoles-derivatives compound. In a article, author is Nikpassand, Mohammad, introduce new discover of the category.

NiFe2O4@(SiO2Pr)-Pr-n@glucose Catalyzed Synthesis of Novel 5-pyrazolin-1,2,4-triazazolidine-3-ones (thiones)

Introduction: NiFe2O4eSiO2nPr@glucose catalyzed synthesis of novel 5-pyrazolin-1,2,4-triazazolidine-3-ones (thiones). Materials and Methods: Amino glucose-functionalized silica-coated NiFe2O4 nanoparticles (NiFe2O4@SiO2 Pr-n@glucose amine or NiFe2O4@SiP@GA) were synthesized and characterized by X-ray powder diffraction (XRD), X-ray spectroscopy (EDX), transmission electron microscope (TEM), field emission scanning electron microscope (FE-SEM), vibrating sample magnetometry (VSM) and fourier transform infrared spectroscopy (FT-IR). Results and Discussion: NiFe2O4@SiP@GA supply an eco-friendly procedure for the synthesis of some novel 5-pyrazolin-1,2,4-triazazolidine-3-ones or thiones through one-pot reaction of thiosemicarbazide (hydrazinecar-bothioamide) and synthetized pyrazole carbaldehydes. These compounds were obtained in high yields in short reaction times. The catalyst could be easily recovered and reused for six cycles with almost consistent activity. The structures of the synthesized 5-pyrazolin-1,2,4-triazazolidine-3-ones or thiones were confirmed by H-1 NMR, C-13 NMR and FTIR spectral data and elemental analyses. Conclusion: In conclusion, we have investigated NiFe2O4@SiO2nPr@amino glucose as a new, eco-friendly, inexpensive, mild and reusable catalyst for the synthesis of 5-pyrazolin-1,2,4-triazazolidine-3-ones or thiones. High yield, a simple work-up procedure, adherence to the basics of green chemistry, environmental friendly and based on natural ingredients, ease of separation and recyclability of the magnetic catalyst and waste reduction are some advantages of this method.

Synthetic Route of 1453-58-3, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 1453-58-3.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics