Chemistry is an experimental science, Product Details of 4233-33-4, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 4233-33-4, Name is 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione, molecular formula is C8H5N3O2, belongs to pyrazoles-derivatives compound. In a document, author is Al-Saheb, Rawan.
Synthesis of new pyrazolone and pyrazole-based adamantyl chalcones and antimicrobial activity
Chalcones and their derivatives are becoming increasingly popular due to their various pharmacological effects. Chalcone molecules may be extracted from natural resources, entirely synthesised, or biosynthesised by modifying the natural ones. In the present study, five pyrazole-based adamantyl heterocyclic compounds were synthesised by condensation of 1-adamantyl chalcone with substituted phenylhydrazine. The products were characterised by using H-1 NMR, C-13 NMR and FT-IR spectroscopy. The microbiological activity of these compounds was investigated against bacteria and fungi. The new compounds showed good to moderate activity against the microbial species used for screening. All developed molecules showed antibacterial activity against Gram-negative and Gram-positive. These molecules showed antifungal activities against Fusarium oxysporum fungus and in a dose-dependent manner, apart from RS-1 molecules which showed compromised antifungal activity and even at a high dose.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 4233-33-4. Product Details of 4233-33-4.
Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics