Synthetic Route of 64781-79-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 64781-79-9, name is 4-Methyl-1H-pyrazol-3-amine, This compound has unique chemical properties. The synthetic route is as follows.
Compound 6 (40 mmol) was dissolved in DMF (100 mL), then 4-methyl-2-aminopyrazole(44 mmol), sodium iodide (48 mmol) and diisopropylethylamine (DIPEA) (48 mmol). the solution was heated to 100 deg.] C, overnight,then cooled to room temperature, diluted with ethyl acetate (200 mL), saturated sodium bicarbonate solution (3 ¡Á 200mL), dried and reducedpressure concentrated and purified by flash chromatography on silica gel, washing wherein release agent, 0% to 4% methanol / dichloromethane to give a white-basedcolor solid 10- (sec-butyl) -5 – ((4-methyl -1H- pyrazol-3-yl) amino) -7 – oxo -2,3,7,10- tetrahydro – [1,4]dioxin [2], 3-H] quinoline-8-carboxylate, 15.09g, yield 91.5%,
The chemical industry reduces the impact on the environment during synthesis 4-Methyl-1H-pyrazol-3-amine. I believe this compound will play a more active role in future production and life.