In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 57097-81-1 as follows. Recommanded Product: 57097-81-1
General procedure: The properly substituted pyrazole (1.0 equiv) was dissolved in anhyd pyridine. DMAP (0.1 equiv) was added, and the reaction mixture was stirred under N2 for 30 min. The appropriate isocyanate (1.1-1.5 equiv) was then added, and the resulting mixture was stirred for 12 h. The solvent was evaporated under reduced pressure and the crude was purified by silica gel column chromatography, eluting with a mixture cyclohexane/EtOAc.
According to the analysis of related databases, 57097-81-1, the application of this compound in the production field has become more and more popular.