Related Products of 16078-71-0, The chemical industry reduces the impact on the environment during synthesis 16078-71-0, name is Ethyl 5-amino-1-phenyl-1H-pyrazole-4-carboxylate, I believe this compound will play a more active role in future production and life.
In the with the condensation tube, thermometer of 250 ml three-neck bottle in, adding […] ethyl acetate (62.1 mmol), phenyl hydrazine (93.2 mmol), ethanol (50 ml), heated to 80 C, reaction 24 h, TLC detection after the reaction, to the room temperature, the solvent is distilled under reduced pressure, the remaining solid without purification directly dissolved in absolute ethanol (200 ml), 80% hydrazine hydrate solution (100 mmol) is slowly added in the reaction solution, heating to reflux 2 hours, TLC detection reaction is over, the system to the room temperature, filtered, washing the solid with ethanol, dry and obtain the product, a white solid, yield 70.5%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Ethyl 5-amino-1-phenyl-1H-pyrazole-4-carboxylate, other downstream synthetic routes, hurry up and to see.