Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 25016-09-5, name is 1,3-Dimethyl-1H-pyrazole-5-carbaldehyde, This compound has unique chemical properties. The synthetic route is as follows., SDS of cas: 25016-09-5
Step 3: Preparation of 3-(2,5-dimethyl-2H-pyrazole-3yl)-2-(4-fluoro phenyl) acrylic acid (16) A mixture of compound 15 (1 gram, 8.0 mmol) and 4-fluorophenyl acetic acid (1.24 grams, 8.0 mmol), acetic anhydride (2 mL) and triethylamine (0.84 mL, 6.0 mmol) was refluxed under nitrogen atmosphere for 5-6 h. The excess of acetic anhydride was distilled out at the same temperature. The mixture was then diluted with water (100 mL) and neutralized with 2N hydrochloric acid. The solid precipitated was filtered and dried under vacuum to afford the title compound 3-(2,5-dimethyl-2H-pyrazole-3yl)-2-(4-fluoro phenyl) acrylic acid (16) 1.4 gram as a pale brown solid. Yield: 67%; 1H NMR (200 MHz, DMSO-d6): delta 12.75 (s, D2O exchangeable) 7.66 (s, 1H), 7.26-7.12 (m, 4H), 5.0 (s, H) 3.84 (s, 3H), 2.05 (s, 3H); Mass (CI method, i-butane): 261 (M+1, 80%); IR: numax (KBr, cm-1): 3440, 1695.
According to the analysis of related databases, 25016-09-5, the application of this compound in the production field has become more and more popular.