Adding a certain compound to certain chemical reactions, such as: 36650-74-5, name is 1H-Pyrazole-3-carbonitrile, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 36650-74-5, SDS of cas: 36650-74-5
Reference Production Example 7-2 1-(hydroxymethyl)-3-cyano-1H-pyrazole The mixture of 0.86 g of 3-cyano-1H-pyrazole and 0.55 g of paraformaldehyde was stirred at 130 C for 7 hours. After the reaction mixture was cooled to room temperature, acetone was added to the reaction mixture. After the mixture was filtered, the filterate was concentrated under reduced pressure to obtain 0.89 g of 1-(hydroxymethyl)-3-cyano-1H-pyrazole. 1H-NMR(DMSO-d6,TMS,delta(ppm)):5.54(2H,s),6.70(1H,d),7.72(1H,d)
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1H-Pyrazole-3-carbonitrile, and friends who are interested can also refer to it.