Synthetic Route of 10250-63-2, These common heterocyclic compound, 10250-63-2, name is Ethyl 1-methyl-3-phenyl-1H-pyrazole-5-carboxylate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A mixture of ester [[10250-63-2]] (1.7 g, 7.4 mmol) and aqueous 1 M KOH (10 mmol) in [ETOH] (20 mL) is stirred for 6 h. The reaction mixture is concentrated, and the residue is partitioned between cold aqueous 1 M HCl and EtOAc. The EtOAc solution is separated. The aqueous solution is further extracted with EtOAc. The combined EtOAc extracts are dried and concentrated to give [10250-64-3] as a powder: MS (ESI-) m/z 185.5.
Statistics shows that Ethyl 1-methyl-3-phenyl-1H-pyrazole-5-carboxylate is playing an increasingly important role. we look forward to future research findings about 10250-63-2.