Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 158001-28-6, name is 5-Amino-1-(tert-butyl)-1H-pyrazole-4-carbonitrile, A new synthetic method of this compound is introduced below., Formula: C8H12N4
To 5-amino-1-tert-butyl-1H-pyrazole-4-cyano (1.1g, 6.75mmol) was added formamide (15mL), heated to reflux for 6 hours to obtain a reaction solution, the reaction solution was treated with ethyl acetate The ester (3¡Á30mL) was extracted, and the resulting organic layer was dried over anhydrous magnesium sulfate. After filtration, the solvent was evaporated under reduced pressure to obtain a brown solid (0.97g, 5.1mmol) (yield 76%).
The synthetic route of 158001-28-6 has been constantly updated, and we look forward to future research findings.