Adding a certain compound to certain chemical reactions, such as: 5334-40-7, name is 4-Nitro-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 5334-40-7, Recommanded Product: 5334-40-7
The compound 2-amino-4-(morpholinomethyl)phenol (2.54 g, 16 mmol) was dissolved.In DMF (15mL),Add 4-nitro-1 hydrogen-pyrazole-3-carboxylic acid (3.4 g, 16 mmol)With HATU (7.4 g, 19.6 mmol), react at room temperature overnight.After the reaction was completed, the solvent was evaporated and ethyl acetate (3¡Á50 mL).Washed with water (2 ¡Á 50 mL), dried over anhydrous sodium sulfate (10 g),Dry to give the crude product (1.5 g), which was used directly to the next step.
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