Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 89501-90-6, name is 1-Methyl-1H-pyrazole-3-sulfonyl chloride, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C4H5ClN2O2S
To a 50 mL flask was added 1-methyl-1H-pyrazole-3-sulfonyl chloride (1.12g, 6.22 mmol), ethyl (4aS,6S)-6-[(2,4-dimethoxyphenyl)methylaminoj -1 -(4-fluorophenyl)-5 ,6,7,8-tetrahydro-4H- benzo[flindazole-4a-carboxylate (lila) (1.57g, 3.11 mmol), DCM (8 mL), and triethylamine (1.73 mL, 12.45 mmol) successively. After the reaction was stirred at 40C for 5 h, it was directly concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (Si02, 40%-65% EtOAc/hexanes, gradient elution) to provide ethyl (4aS,6S) -6-[(2,4-dimethoxyphenyl)methyl-( 1- methylpyrazol-3 -yl)sulfonyl-aminoj -1 -(4-fluorophenyl)-5 ,6,7, 8-tetrahydro-4H-benzo [flindazole-4a- carboxylate (ilib) (1.86g, 92% yield) as a yellow solid. m/z(ESI, +ve ion) = 650.3 [M+Hj.
According to the analysis of related databases, 89501-90-6, the application of this compound in the production field has become more and more popular.