Features of reactions of (E)-1-(β-aroylvinyl)pyridinium bromides with binucleophiles was written by Khachikyan, R. Dzh.;Ovakimyan, Z. G.;Panosyan, G. A.;Tamazyan, R. A.;Ayvazyan, A. G.. And the article was included in Russian Journal of General Chemistry in 2016.Category: pyrazoles-derivatives This article mentions the following:
Reactions of (E)-1-(β-aroylvinyl)pyridinium bromides with hydrazine led to the formation of pyrazole derivatives I•HCl (R = Me, Cl, Br) regardless of pH and a solvent nature. The salts reacted with thiourea via intermediate formation of 4-arylpyrimidine-2-thiol to gave (Z)-2-[(β-aroylvinyl)sulfanyl]-4 arylpyrimidines II (R = Me, Cl, Br). In the case of N,N’-diphenylthiourea the reaction provided 6-aryl-3-aroyl-1-phenylpyridinium bromides III•Br– (R = Me, Cl, Br). Pyridine hydrobromide liberated in the reaction course had a major influence on the process chemoselectivity. In the experiment, the researchers used many compounds, for example, 3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9Category: pyrazoles-derivatives).
3-(4-Bromophenyl)-1H-pyrazole (cas: 73387-46-9) belongs to pyrazole derivatives. The 1H-pyrazole provides an excellent means by which to provide the requisite hydrogen bond acceptor–donor motifs, whether as a monocyclic ring or as a fused indazole ring. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.Category: pyrazoles-derivatives
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics