Bridgehead nitrogen heterocycles. Part II. Reactions of 4-bromo-3-methyl-1-substituted-5-pyrazolones with 4-amino-3-mercapto-5-substituted-s-triazoles and cyclic thioureas was written by Chadha, Vijay K.;Sharma, G. R.. And the article was included in Journal of the Indian Chemical Society in 1990.HPLC of Formula: 51395-52-9 This article mentions the following:
Bromomethylpyrazolones I (R = H, Ph) undergo cyclocondensation with aminomercaptotriazoles II (R1 = Me, Et, Pr, Ph, 2-HOC6H4, 3-O2NC6H4) to give pyrazolotriazolothiadiazines III. I also reacts with cyclic thioureas, e.g. 2-mercapto-1-imidazoline gave pyrazoloimidazolothiazole IV. In the experiment, the researchers used many compounds, for example, 4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9HPLC of Formula: 51395-52-9).
4-Bromo-3-methyl-1H-pyrazol-5(4H)-one (cas: 51395-52-9) belongs to pyrazole derivatives. The 1H-pyrazole provides an excellent means by which to provide the requisite hydrogen bond acceptor–donor motifs, whether as a monocyclic ring or as a fused indazole ring. Pyrazole rings have been used as core components of several leading non-steroidal anti-inflammatory drugs (NSAIDs) and antihypertensive drugs. It has also been found to be useful as a bifunctional ligand for metal catalysis.HPLC of Formula: 51395-52-9
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics