A new procedure for the synthesis of 4H-pyrazolo[1,5-c][1,3,5]thiadiazine-4-thiones was written by Vicentini, C. B.;Veronese, A. C.;Guarneri, M.;Manfrini, M.;Giori, P.;Guccione, S.. And the article was included in Journal of Heterocyclic Chemistry in 1994.Product Details of 141459-53-2 This article mentions the following:
Thiation of pyrazolyl amides I (R = alkyl, 4-halophenyl; R1 = CMe3; X = O) by the Lawesson reagent afforded I (same R, R1; X = S). Heating the thiocarboxamides in formic acid gave the N-dealkylated thiocarboxamides (I; R = alkyl, 4-halophenyl; R1 = H; X = S), which were cyclized with thiophosgene to give the title compounds (II). In the experiment, the researchers used many compounds, for example, 1-(tert-Butyl)-3-methyl-1H-pyrazol-5-amine (cas: 141459-53-2Product Details of 141459-53-2).
1-(tert-Butyl)-3-methyl-1H-pyrazol-5-amine (cas: 141459-53-2) belongs to pyrazole derivatives. Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. Pyrazoles can be selectively lithiated at different carbons and subsequently react with electrophiles depending on the substitution patterns.Product Details of 141459-53-2
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics