Idemudia, Omoruyi G. published the artcileMetal complexes of new bioactive pyrazolone phenylhydrazones; crystal structure of 4-acetyl-3-methyl-1-phenyl-2-pyrazoline-5-one phenylhydrazone Ampp-Ph, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, the publication is International Journal of Molecular Sciences (2016), 17(5), 687/1-687/24, database is CAplus and MEDLINE.
The condensation reaction of phenylhydrazine and dinitrophenylhydrazine with 4-acetyl and 4-benzoyl pyrazolone precipitated air-stable acetyldinitrophenylhydrazone Ampp-Dh, benzoylphenylhydrazone Bmpp-Ph and benzoyldinitrophenylhydrazone Bmpp-Dh in their keto imine form; a study inspired by the burning interest for the development of new bioactive materials with novel properties that may become alternative therapeutic agents. Elemental anal., FTIR, 1H, and 13C NMR, and mass spectroscopy have been used to justify their proposed chem. structures, which were in agreement with the single crystal structure of Bmpp-Dh earlier reported according to X-ray crystallog. The single crystal structure of 4-acetyl-3-methyl-1-phenyl-pyrazoline-5-one phenylhydrazone Ampp-Ph, which crystallizes in a triclinic crystal system with a P-1 (Number 2) space group is presented. Octahedral Mn(II), Ni(II), Co(II), and Cu(II) complexes of these resp. ligands with two mols. each of the bidentate Schiff base, coordinating to the metal ion through the azomethine nitrogen C=N and the keto oxygen C=O, which were afforded by the reaction of aqueous solutions of the corresponding metal salts with the ligands are also reported. Their identity and proposed structures were according to elemental anal., FTIR spectroscopy, UV-VIS spectrophotometry (electronic spectra) and Bohr magnetic moments, as well as thermogravimetric anal. (TGA) results. A look at the antibacterial and antioxidant activities of synthesized compounds using the methods of the disk diffusion against some selected bacterial isolates and 1,1-diphenyl-2-picryl-hydrazil (DPPH) resp., showed biol. activities in relation to employed standard medicinal drugs.
International Journal of Molecular Sciences published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Recommanded Product: 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one.
Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics