Dorgan, Roderick J. J.’s team published research in Journal of Chemical Research, Synopses in | CAS: 3553-12-6

Dorgan, Roderick J. J. published the artcileN-Alkyl and N-acyl derivatives of 3(5)-aminopyrazole, Safety of 3-Acetamidopyrazole, the publication is Journal of Chemical Research, Synopses (1979), 198, database is CAplus.

3(5)-Aminopyrazole (I) underwent benzylation on the exocyclic N to give II [R = H, R¹ = R² = CH₂Ph; R = R¹ = H, R² = CH₂Ph (III)] whereas acetylation gave II (R = R¹ = Ac, R² = H), which on subsequent benzylation gave II (R = CH₂Ph, R¹ = Ac, R² = H) and IV (R = CH₂Ph, R¹ = H, R² = Ac) (V). In the presence of MeCOCH₂CO₂Et, III gave the pyrazolo[1,5-a]pyrimidine VI (R = CH₂Ph) which was debenzylated to VI (R = H). PhCH₂NHNH₂ reacted with CH₂:CClCN to give IV (R = CH₂Ph, R¹ = R² = H) which on acetylation gave V. I with phthalic anhydride gave II (R = H, NR¹R² = phthalimido) which on benzylation and benzyloxymethylation gave II (R = CH₂Ph, R¹R² as before) and IV (R = CH₂OCH₂Ph, R¹R² as before), resp.

Journal of Chemical Research, Synopses published new progress about 3553-12-6. 3553-12-6 belongs to pyrazoles-derivatives, auxiliary class Pyrazole,Amine,Amide, name is 3-Acetamidopyrazole, and the molecular formula is C5H7N3O, Safety of 3-Acetamidopyrazole.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics