Purohit, Vishal B.’s team published research in Catalysis Science & Technology in 5 | CAS: 14580-22-4

Catalysis Science & Technology published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Quality Control of 14580-22-4.

Purohit, Vishal B. published the artcilePalladium N-heterocyclic carbene catalyzed regioselective C-H halogenation of 1-aryl-3-methyl-1H-pyrazol-5(4H)-ones using N-halosuccinimides (NXS), Quality Control of 14580-22-4, the publication is Catalysis Science & Technology (2015), 5(6), 3113-3118, database is CAplus.

A novel palladium N-heterocyclic carbene [Pd(NHC)Cl2] complex of vitamin B1 was synthesized and characterized by 1H NMR, EDX, FT-IR and UV-visible spectroscopy. The complex was used as a catalyst for regioselective ortho-C-H chlorination/bromination of 1-aryl-3-methyl-1H-pyrazol-5(4H)-ones via C-H bond activation utilizing Ag2O as the effective terminal additive. The catalyst was easy to prepare, efficient and found to be highly regioselective, affording the target products in moderate to excellent yields.

Catalysis Science & Technology published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Quality Control of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics