Vernier, William F.’s team published research in Tetrahedron Letters in 58 | CAS: 930-36-9

Tetrahedron Letters published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C15H12O8, Computed Properties of 930-36-9.

Vernier, William F. published the artcileRegioselective palladium-catalyzed C-H arylation of 4-alkoxy and 4-thioalkyl pyrazoles, Computed Properties of 930-36-9, the publication is Tetrahedron Letters (2017), 58(49), 4587-4590, database is CAplus.

Alkoxy- and alkylthiopyrazoles such as 4-benzyloxy-1-methylpyrazole underwent regioselective arylation with aryl and heteroaryl bromides in the presence of Pd(OAc)2 and either SPhos or QPhos in 1,4-dioxane at 70-90 °C to yield arylpyrazoles such as I and an arylimidazole in 19-88% yields; 1-methylpyrazole, 4-chloro-1-methylpyrazole, 1-phenyl-4-pyrazolecarboxaldehyde, and 1-methylimidazole also underwent arylation under similar conditions but required higher temperatures Bromoaralkyl pyrazolyl ethers and thioethers such as 4-(2-bromobenzyloxy)-1-methylpyrazole underwent intramol. arylation to yield fused pyrazoles such as pyrazoloisobenzopyran II in 34-93% yields.

Tetrahedron Letters published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C15H12O8, Computed Properties of 930-36-9.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics