Martins, Marcos A. P. et al. published their research in Journal of Heterocyclic Chemistry in 1999 | CAS: 17355-75-8

Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate (cas: 17355-75-8) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, neuroleptic, anticonvulsant, monoamine oxidase inhibitory, antidiabetic and antibacterial activities.Product Details of 17355-75-8

Haloacetylated enol ethers. 11. Synthesis of 1-methyl- and 1-phenyl pyrazole-3(5)-ethyl esters. A one-pot procedure was written by Martins, Marcos A. P.;Freitag, Rogerio A.;Da Rosa, Adriano;Flores, Alex F. C.;Zanatta, Nilo;Bonacorso, Helio G.. And the article was included in Journal of Heterocyclic Chemistry in 1999.Product Details of 17355-75-8 The following contents are mentioned in the article:

Me and phenylpyrazole Et esters I [R = Me, Ph; R1 = Me, Ph, EtO2C; R2 = H, Me; R1R2 = (CH2)4; R3 = EtO2C, Me, Ph; R2R3 = (CH2)4] are prepared by the cyclocondensation of β-alkoxyvinyl trichloromethyl ketones II [R4 = Me, Et; R5 = Me, Ph; R6 = H, Me; R5R6 = (CH2)4] with Me and Ph hydrazine hydrochloride in a one-pot reaction under mild conditions in 60-89% with a variety of enol ethers. Effects of hydrazine and β-alkoxyvinyl trichloromethyl ketone substituents on the regiochem. of pyrazole cyclization were observed This study involved multiple reactions and reactants, such as Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate (cas: 17355-75-8Product Details of 17355-75-8).

Ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate (cas: 17355-75-8) belongs to pyrazole derivatives. Pyrazoles, a five-membered heterocycle containing two adjacent nitrogen atoms, are the core structures found in a number of molecules that possess a wide range of pharmaceutical and agricultural activities. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, sedative, muscle relaxant, neuroleptic, anticonvulsant, monoamine oxidase inhibitory, antidiabetic and antibacterial activities.Product Details of 17355-75-8

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics