Li, Yong-xiang’s team published research in Fluid Phase Equilibria in 473 | CAS: 930-36-9

Fluid Phase Equilibria published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Product Details of C4H6N2.

Li, Yong-xiang published the artcileSolubility of 1-methyl-4-nitropyrazole in seventeen pure solvents at temperatures from 283.15 K to 323.15 K, Product Details of C4H6N2, the publication is Fluid Phase Equilibria (2018), 80-89, database is CAplus.

Knowledge of solubility for 1-methyl-4-nitropyrazole (1-M-4-NP) in different solvents is important for its purification and further theor. studies. In this paper, the solubility of 1-M-4-NP in toluene, 1,2-dichlorobenzene, water, methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, 1-pentanol, 2-pentanol, Me acetate, Et acetate, acetone, butanone, acetic acid and acetonitrile were determined at T = (283.15, 288.15, 293.15, 298.15, 303.15, 308.15, 313.15, 318.15 and 323.15) K under atm. pressure (P = 0.1 MPa) by a gravimetric method. The results showed that the solubility increases with rise of temperature in all selected solvents and the solubility in acetone increases fastest. In alc. solvents, the solubility decreases with the increasing in the number of carbon atoms in the alc. Addnl., melting temperature and fusion enthalpy of 1-M-4-NP were measured by differential scanning calorimetry (DSC). Besides, the solubility values were correlated by the modified Apelblat equation, the polynomial empirical equation, λh equation and NRTL model. Since the correlation coefficients (R2) of the four models are greater than 0.9900 and the largest values of the root-mean-square was 7.00 × 10-2, four correlation models can be adopted to correlate the solubility data. On the basis of the NRTL model, the dissolution thermodn. properties, including enthalpy, entropy and Gibbs energy were calculated and discussed as well according to the exptl. data, from which we conclude that the dissolution of 1-M-4-NP is an spontaneous process. Furthermore, solubility values and thermodn. relations of 1-M-4-NP in selected solvents would be invoked as fundamental data and models regarding the purification process of 1-M-4-NP.

Fluid Phase Equilibria published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Product Details of C4H6N2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics