Labroli, Marc A.’s team published research in Tetrahedron Letters in 57 | CAS: 930-36-9

Tetrahedron Letters published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Related Products of pyrazoles-derivatives.

Labroli, Marc A. published the artcileA convergent preparation of the CHK1 inhibitor MK-8776 (SCH 900776), Related Products of pyrazoles-derivatives, the publication is Tetrahedron Letters (2016), 57(24), 2601-2603, database is CAplus.

This Letter describes the development of a convergent, efficient route to the CHK1 inhibitor MK-8776, I. This synthetic approach relies upon the cyclization of a bispyrazole adduct 10 with a optically pure β-keto nitrile 9 to construct the pyrazolo[1,5-a]pyrimidine scaffold in a single step.

Tetrahedron Letters published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Related Products of pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics