Hack, Daniel published the artcileAsymmetric Synthesis of Spiropyrazolones by Sequential Organo- and Silver Catalysis, Application In Synthesis of 14580-22-4, the publication is Angewandte Chemie, International Edition (2016), 55(5), 1797-1800, database is CAplus and MEDLINE.
A stereoselective one-pot synthesis of spiropyrazolones, e.g., I, through an organocatalytic asym. Michael addition and a formal Conia-ene reaction has been developed. Depending on the nitroalkene, the 5-exo-dig-cyclization could be achieved by silver-catalyzed alkyne activation or by oxidation of the intermediate enolate. The mechanistic pathways have been investigated using computational chem. and mechanistic experiments
Angewandte Chemie, International Edition published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Application In Synthesis of 14580-22-4.
Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics