Belen’kii, L. I.’s team published research in Russian Chemical Bulletin in 65 | CAS: 930-36-9

Russian Chemical Bulletin published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Product Details of C4H6N2.

Belen’kii, L. I. published the artcileAlternative mechanisms of electrophilic substitution in azole series, Product Details of C4H6N2, the publication is Russian Chemical Bulletin (2016), 65(6), 1441-1447, database is CAplus.

Data on three mechanisms of aromatic electrophilic substitution in azole series were presented. First of them is similar to an ordinary addition-elimination mechanism including the formation of a cationic σ-complex (Wheland intermediate). The second mechanism is realized according to the elimination-addition scheme and includes a protonation or a formation of a complex on the pyridine N atom, proton abstraction from the C atom adjacent to the above N atom, and addition of a cationoid reagent to the ylide (carbene) formed. The third mechanism proposed by the present authors can be realized for azoles having three and two N atoms of the pyridine type. It does not require the preliminary N-protonation or complex formation and occurs due to a strong electron withdrawing effect of several pyridine atoms, resulting in the CH-deprotonation followed by the interaction of the carbanion formed with a cation under mild conditions.

Russian Chemical Bulletin published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Product Details of C4H6N2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics