Liu, Chong-Bo’s team published research in Journal of Heterocyclic Chemistry in 49 | CAS: 4551-69-3

Journal of Heterocyclic Chemistry published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Product Details of C17H14N2O2.

Liu, Chong-Bo published the artcileSyntheses, Characterization, and Antibacterial Activities of Four New Schiff Base Compounds Derived from 1-Phenyl-3-methyl-4-benzoyl-2-pyrazolin-5-one, Product Details of C17H14N2O2, the publication is Journal of Heterocyclic Chemistry (2012), 49(4), 839-844, database is CAplus.

Four new Schiff bases were designed and synthesized. 5-Methyl-4-(4-aminophenylamino-phenyl-methylene)-2-phenyl-2,4-dihydro-pyrazol-3-one (compound 1) and 5-methyl-4-(2-aminophenylamino-phenyl-methylene)-2-phenyl-2,4-dihydro-pyrazol-3-one (compound 2) were synthesized by interaction of 1-phenyl-3-methyl-4-benzoyl-2-pyrazolin-5-one (PMBP) with o- and p-phenylenediamine, resp.; 4,4′-(1,2-phenylenebis(azanediyl)bis(phenylmethanylylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one) (compound 3) and 5-methyl-4-(phenyl(2-((3-phenylallylidene)amino)phenylamino)methylene)-2-phenyl-2,4-dihydro-pyrazol-3-one (compound 4) were synthesized by interaction of compound 2 with PMBP and cinnamaldehyde in an ethanolic medium, resp. The mol. structures of the title compounds were first characterized by single-crystal X-ray diffraction, mass spectrometry, and elemental anal. The title compounds were tested for antibacterial activity (Escherichia coli, Staphylococcus aureus, and Bacillus subtilis) by disk diffusion method.

Journal of Heterocyclic Chemistry published new progress about 4551-69-3. 4551-69-3 belongs to pyrazoles-derivatives, auxiliary class Benzenes, name is 4-Benzoyl-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, and the molecular formula is C17H14N2O2, Product Details of C17H14N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics