Fu, Lili published the artcileSynthesis of sulfonamides from azoles and sodium sulfinates at ambient temperature, Name: 4-Bromo-1-tosyl-1H-pyrazole, the main research area is oxidative amination azole sodium sulfinate NBS NIS sulfonamide synthesis; sulfur nitrogen bond formation azole sodium sulfinate.
NBS or NIS mediated direct S-N bond formation between azoles and sodium sulfinates is described. The reaction shows good substrate scope and tolerates a wide range of functionalities in both azoles and sodium sulfinate substrates. Pyrazoles are also suitable for this method, various 4-halopyrazoles derivatives were obtained by using N-halosuccinimide (NXS) as the halogen source. Thus, e.g., oxidative amination of benzimidazole with sodium p-tolylsulfinate using NBS as oxidant in 1,4-dioxane afforded 1-tosylbenzimidazole (93%).
Tetrahedron published new progress about Atom economy. 116228-41-2 belongs to class pyrazoles-derivatives, name is 4-Bromo-1-tosyl-1H-pyrazole, and the molecular formula is C10H9BrN2O2S, Name: 4-Bromo-1-tosyl-1H-pyrazole.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics