Nishioka, Masanori published the artcileInduction of resistance against rice blast disease by a novel class of plant activator, pyrazolecarboxylic acid derivatives, Category: pyrazoles-derivatives, the main research area is pyrazolecarboxylate derivative preparation rice blast disease resistance.
Synthesis and characterization of anti-rice blast activity of pyrazole derivatives was described. Structure-activity relationship study indicated that a carboxyl group at 5-position of 1-methyl-1H-pyrazole played an important role in the activity and that a halogen atom such as a chlorine or bromine at 3-position enhanced the activity. Among the derivatives, 3-chloro-1-methyl-1H-pyrazole-5-carboxylic acid (CMPA) exhibited the highest anti-rice blast activity with the ED80 (80% ED, the concentration needed for 80% inhibition of disease development) of 0.05 mg/pot. CMPA did not have any significant effects on the hyphal growth, spore germination, and appressorium formation of Pyricularia oryzae, suggesting that CMPA induces systemic acquired resistance in rice plants.
Journal of Pesticide Science (Tokyo, Japan) published new progress about Agrochemical fungicides. 63425-54-7 belongs to class pyrazoles-derivatives, name is 3-Chloro-1-methyl-1H-pyrazole, and the molecular formula is C4H5ClN2, Category: pyrazoles-derivatives.
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics