Pyrazole is an organic compound with the formula C3H3N2H. It is a heterocycle characterized by a 5-membered ring of three carbon atoms and two adjacent nitrogen atoms, which are in ortho-substitution. 37622-90-5, formula is C6H8N2O2, Name is Ethyl 4-pyrazolecarboxylate. Pyrazoles are a class of compounds that have the ring C3N2 with adjacent nitrogen atoms.Notable drugs containing a pyrazole ring are celecoxib (celebrex) and the anabolic steroid stanozolol. Recommanded Product: Ethyl 4-pyrazolecarboxylate.
Lu, Ke;Xue, Chu-ran;Qiao, Hui;Liu, Shu-wen;Xu, Xiang-wen research published 《 Analysis of aroma composition of litchi ice wine by different extraction fibers》, the research content is summarized as follows. The aroma compounds of litchi ice wine were analyzed by head-space solid-phase micro-extraction (HSSPME) coupled to gas chromatog.-mass spectrometry (GC-MS). The efficiency of three different extraction fibers was evaluated by comparing the number, chem. group and cumulative area normalization value (CANV) of the extracted compounds The results indicated that the extraction efficiency of aroma compounds were very different in litchi ice wine because of different fibers. Totally 62, 56 and 52 aroma compounds in litchi ice wine were extracted through PA, CAR/PDMS and DNB/CAR/PDMS, resp. The major constituents were esters, alcs., acids, ketones, aldehydes, and a few terpenes. The most important aroma compounds were Et caprylate (38.96%), Et caprate (25.14%), Et caproate (9.31%), isoamyl alc. (7.89%), Me methacrylate (1.52%), Et laurate (1.49%), 3-furaldehyde (1.26%), decanoic acid (1.25%), benzyl alc. (1.21%), damascenone (1.21%), and phenethyl alc. (0.30%). The anal. of cumulative area normalization value indicated that 85 μm PA was more sensitive to extract acids but least sensitive to other compounds, 75 μm CAR/PDMS was more sensitive to esters and alcs., and 50/30 μm DNB/CAR/PDMS was more sensitive to ketones and aldehydes. Considering all factors above, 75 μm CAR/PDMS was the optimal fiber for the extraction of aroma compounds in litchi ice wine.
37622-90-5, Ethyl 4-pyrazolecarboxylate, also known as Ethyl pyrazole-4-carboxylate, is a useful research compound. Its molecular formula is C6H8N2O2 and its molecular weight is 140.14 g/mol. The purity is usually 95%.
Ethyl pyrazole-4-carboxylate is a low yield, transition metal salt that is used in the synthesis of pyrazoles. It can be synthesized by the reaction of sodium ethoxide with ethyl chloroformate and a Grignard reagent. Sodium ethoxide is added to a suspension of sodium chloride and dried ethyl chloroformate, followed by addition of magnesium turnings. The mixture is refluxed for one hour, cooled, and filtered to give crystals. Ethyl pyrazole-4-carboxylate is used in the preparation of ethyl esters from aliphatic alcohols by reacting with boron trichloride or phosphorus pentachloride. It participates in certain chemical reactions as a byproduct and can damage equipment during chemical reactions. The yield of this compound can be increased by using an excess amount of Grignard reagent or adding hexamethylenetetramine to the reaction mixture, Recommanded Product: Ethyl 4-pyrazolecarboxylate
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics