Pei, Congcong; Chen, Xiaoyu; Li, Linlin; Li, Jingya; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng published their research in Tetrahedron Letters in 2021. The article was titled 《Copper-catalyzed C3-amination of quinoxalin-2(1H)-ones: Using Selectfluor as a mild oxidant》.Application In Synthesis of 3-(Trifluoromethyl)-1H-pyrazole The article contains the following contents:
A practical and efficient route for copper-catalyzed C-3 amination of quinoxalin-2(1H)-ones with easily available azoles as nitrogen sources and Selectfluor as mild oxidant was developed. The transformation featured at. economy, simple operation, broad substrate scope, and moderate to excellent yields. After reading the article, we found that the author used 3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4Application In Synthesis of 3-(Trifluoromethyl)-1H-pyrazole)
3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4) belongs to pyrazoles. The application of pyrazole derivatives in the development of anticancer agents has been thoroughly investigated and verified. Moreover, the medicinal features of a number of natural products incorporating pyrazole moiety such as pyrazofurin, pyrazofurin B, pyrazole-3(5)-carboxylic acid and 4-methylpyrazole-3(5)-carboxylic acid have been reported.Application In Synthesis of 3-(Trifluoromethyl)-1H-pyrazole
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics