Formula: C4H3F3N2In 2015 ,《Ruthenaphosphaalkenyls: synthesis, structures, and their conversion to η2-phosphaalkene complexes》 was published in Organometallics. The article was written by Greenacre, Victoria K.; Trathen, Nicola; Crossley, Ian R.. The article contains the following contents:
The ruthenaphosphaalkenyls [Ru{P:CH(SiMe2R)}Cl(CO)(PPh3)2] (R = Me, Ph, Tol) have been prepared in good yield by the facile hydroruthenation of the resp. phosphaalkynes, RMe2SiCP, with [RuHCl(CO)(PPh3)3]; all three compounds have been structurally characterized in the solid state. Complemented by DFT studies of these, and the precedent [Ru{P:CH(tBu)}Cl(CO)(PPh3)2], the phosphaalkenyl moieties have been established unequivocally to behave as one-electron donors to the coordinately unsaturated, 15-electron “”RuCl(CO)(PPh3)2″” fragment, corroborating an earlier demonstration of nucleophilic character at phosphorus within the tert-Bu system. Notwithstanding, the ruthenaphosphaalkenyls are shown to react with the nucleophiles Lipz’ (pz’ = pz, pz*, pzH,CF3, pzMe,CF3) to afford the η1,η2-chelated pyrazolylphosphaalkene complexes [Ru{η1-N:η2-P,C-P(pz’):CH(R)}(CO)(PPh3)2], which feature a three-membered metallacyclic (Ru-C-P) core. The nature of these novel compounds is discussed, alongside preliminary insight into the process by which they are formed. The results came from multiple reactions, including the reaction of 3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4Formula: C4H3F3N2)
3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Formula: C4H3F3N2
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics