Sun, Mingli; Zhou, Yuhui; Li, Laiqiang; Wang, Lei; Ma, Yongmin; Li, Pinhua published an article in 2021. The article was titled 《Electrochemically promoted C-3 amination of 2H-indazoles》, and you may find the article in Organic Chemistry Frontiers.Computed Properties of C5H6N2O2 The information in the text is summarized as follows:
A metal-free and external oxidant-free electrochem. method for the C-3 amination of 2H-indazoles was reported for the synthesis of indazolyl-amines I [R = n-Bu, 1-pyrazolyl, morpholino, etc.; R1 = H, 5-F, 6-Br, etc.; R2 = Ph, 1-naphthyl, 2-pyridyl, etc.]. The protocol employed com. available azoles and aliphatic amines as amination reagents and had a broad substrate scope, providing the corresponding C3-amination products in high yields at room temperature Mechanistic studies indicated that an oxidative addition/elimination sequence was involved under electrochem. conditions. In the part of experimental materials, we found many familiar compounds, such as Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4Computed Properties of C5H6N2O2)
Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4) belongs to pyrazoles. The application of pyrazole derivatives in the development of anticancer agents has been thoroughly investigated and verified. Moreover, the medicinal features of a number of natural products incorporating pyrazole moiety such as pyrazofurin, pyrazofurin B, pyrazole-3(5)-carboxylic acid and 4-methylpyrazole-3(5)-carboxylic acid have been reported.Computed Properties of C5H6N2O2
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics