Reference of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleIn 2009 ,《A convenient and rapid approach for the synthesis of 1-benzyl-3-heterocyclic pyrazoles》 appeared in Tetrahedron Letters. The author of the article were Curtis, Michael P.; Sammons, Matthew F.; Piotrowski, David W.. The article conveys some information:
A variety of 1-benzyl-3-hetarylpyrazoles were rapidly assembled by a 2-step N-benzylation/Suzuki coupling sequence using a 3-pyrazolylboronate and benzyl bromides as starting compounds A 1-pot variation of this sequence is demonstrated. The results came from multiple reactions, including the reaction of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole(cas: 844501-71-9Reference of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole)
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole(cas: 844501-71-9) belongs to pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, antipyretic, neuroleptic, anticonvulsant, antiarrhythmic, sedative, muscle relaxant, monoamine oxidase inhibitory, anti-inflammatory, antidiabetic and antibacterial activities. Reference of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics