Zhang, Juan’s team published research in Organic Letters in 2021-11-05 | 118430-74-3

Organic Letters published new progress about 1,3-Dipolar cycloaddition reaction. 118430-74-3 belongs to class pyrazoles-derivatives, and the molecular formula is C7H11N3, Application of C7H11N3.

Zhang, Juan; Li, Xianfeng; Wei, Haimei; Li, Yangfeng; Zhang, Gong; Li, Yizhou published the artcile< Sequential DNA-Encoded Building Block Fusion for the Construction of Polysubstituted Pyrazoline Core Libraries>, Application of C7H11N3, the main research area is aryl amine DNA encoded aldehyde cyclization; encoded DNA tetrazole preparation alkene cycloaddition; DNA encoded pyrazoline preparation.

Herein, a sequential DNA-encoded synthesis strategy for polysubstituted pyrazoline heterocycles, which fuses a broad panel of aldehydes, aryl amines, and alkenes as building blocks was reported. Furthermore, mock library synthesis and selection demonstrated the ability of the method to produce DNA-encoded focused libraries with highly functionalized pyrazoline cores.

Organic Letters published new progress about 1,3-Dipolar cycloaddition reaction. 118430-74-3 belongs to class pyrazoles-derivatives, and the molecular formula is C7H11N3, Application of C7H11N3.

Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics