Perez, Jorge D.; Yranzo, Gloria I.; Phagouape, Leonardo M. published an article on February 28 ,1986. The article was titled 《Influence of N-substitution in the FVT (flash vacuum thermolysis) of pyrazoles》, and you may find the article in Bulletin de la Societe Chimique de France.Safety of 1-Butyl-1H-pyrazole The information in the text is summarized as follows:
Flash vacuum thermolysis of 1-ethyl-, 3,5-dimethyl-1-ethyl- (I), 1-butyl-, 1-tert-butyl-, 3,5-dimethyl-1-phenyl- and 1-phenylpyrazole was studied. In the N-alkyl derivatives, pyrazole elimination and olefin formation were found. In contrast, Ph derivatives afforded isomerization and nitrogen extrusion. Kinetic parameters for compound I are described and a general mechanism including the N-H derivatives is discussed. In the part of experimental materials, we found many familiar compounds, such as 1-Butyl-1H-pyrazole(cas: 52096-24-9Safety of 1-Butyl-1H-pyrazole)
1-Butyl-1H-pyrazole(cas: 52096-24-9) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Safety of 1-Butyl-1H-pyrazole
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics