In 2014,Angewandte Chemie, International Edition included an article by O’Brien, Alexander G.; Maruyama, Akinobu; Inokuma, Yasuhide; Fujita, Makoto; Baran, Phil S.; Blackmond, Donna G.. Category: pyrazoles-derivatives. The article was titled 《Radical C-H functionalization of heteroarenes under electrochemical control》. The information in the text is summarized as follows:
Electrochem. reactions are shown to be effective for the C-H functionalization of a number of heterocyclic substrates that are recalcitrant to conventional peroxide radical initiation conditions. Monitoring reaction progress under electrochem. conditions provides mechanistic insight into the C-H functionalization of a series of heterocycles of interest in medicinal chem. In addition to this study using Methyl 1-methyl-1H-pyrazole-4-carboxylate, there are many other studies that have used Methyl 1-methyl-1H-pyrazole-4-carboxylate(cas: 5952-93-2Category: pyrazoles-derivatives) was used in this study.
Methyl 1-methyl-1H-pyrazole-4-carboxylate(cas: 5952-93-2) belongs to pyrazoles. Pyrazoles and their related multiring analogs are common elements of a wide variety of bioactive compounds. These ring structures are rare in nature. A consequence of this is that they have previously been thought to be poor moieties to include in potential new drugs. Category: pyrazoles-derivatives
Referemce:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics