Day: October 9, 2021

Safety of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Authors Zhou, L; Yan, JX; Huang, JL; Wang, HB; Wang, XG; Wang, ZJ in ELSEVIER SCI LTD published article about in [Zhou, Liang; Yan, Junxiao; Huang, Julong; Wang, Hongbo; Wang, Xingang; Wang, Zhenjun] Changan Univ, Sch Mat Sci & Engn, Xian 710064, Peoples R China; [Zhou, Liang; Wang, Hongbo; Wang, Xingang; Wang, Zhenjun] Changan Univ, Minist Educ, Engn Res Ctr Transportat Mat, Xian 710061, Peoples R China in 2021, Cited 46. The Name is 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Through research, I have a further understanding and discovery of 83-10-3

Here in, the effects of FeSiAl particle size on the dielectric and microwave absorption properties of FeSiAl/Al2O3 composites were studied. FeSiAl/Al2O3 composites containing 18-25 mu m, 25-48 mu m, and 48-75 mu m FeSiAl particles were prepared by hot-pressed sintering based on uniformly mixed FeSiAl and Al2O3 powders. Results show that the real permittivity and the imaginary permittivity are significantly promoted with increasing FeSiAl particle size, which is ascribed to the enhanced interfacial polarization and conductance loss. In addition, the favorable matching impedance and suitable attenuation coefficient enabled the composite containing 25-48 mu m FeSiAl powder to show a minimum reflection loss of -34.4 dB at 11.7 GHz and an effective absorption bandwidth (<-10 dB) of 1.4 GHz in 11.0-12.4 GHz, when the thickness is 1.1 mm. By adjusting the thickness to 1.4 mm, the effective absorption bandwidth of the composite reaches a maximum value of 2.0 GHz in the 8.3-10.3 GHz range, indicating tunable, strong, and highly efficient microwave absorption performance. Safety of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. About 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid, If you have any questions, you can contact Zhou, L; Yan, JX; Huang, JL; Wang, HB; Wang, XG; Wang, ZJ or concate me.

Reference:
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Huang Daowei; Wang Wenya; Zhang Zhiguo; Jiang Ling; (45 pag.)CN107286140; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Vynohradov, OS; Pavlenko, VA; Naumova, DD; Partsevska, SV; Shova, S; Safarmamadov, SM in [Vynohradov, Oleksandr S.; Pavlenko, Vadim A.; Naumova, Dina D.; Partsevska, Sofiia, V] Taras Shevchenko Natl Univ Kyiv, Dept Chem, Volodymyrska Str 64-13, UA-01601 Kiev, Ukraine; [Shova, Sergiu] Poni Petru Inst Macromol Chem, Voda 41A, Iasi 700487, Romania; [Safarmamadov, Safarmamad M.] Tajik Natl Univ, Dept Chem, 17 Rudaki Ave, Dushanbe 734025, Tajikistan published Crystal structure of bis{mu-2-[bis(2-hydroxyethyl)-amino]ethanolato]bis(mu-3,5-aimethyipyrazolato)-tricopper(II) dibromide sesquihyarate in 2020.0, Cited 22.0. Safety of 3,5-Dimethyl-1H-pyrazole. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

In the title bicyclic trinuclear pyrazolate aminoalcohol complex, [Cu-3(C5H7N2)(2)-(C6H14NO3)(2)]Br-2 center dot 1.5H(2)O, the central Cu atom lies on a center of symmetry and is involved in the formation of two five-membered rings. It has a coordination number of 4, is in a distorted tetrahedral environment and is connected by the bridging oxygen atoms of the deprotonated OH groups of different aminoalcohol groups, and by the N atoms of deprotonated dimethylpyrazole ligands. The peripheral Cu atom is in a trigonal-bipyramidal coordination environment formed by the nitrogen atom of the deprotonated bridging dimethylpyrazole unit, the bridging oxygen atom of the deprotonated OH group, two oxygen atoms of the protonated hydroxy groups and the nitrogen atom of triethanolamine. One of the C atoms and the Br- anion were found to be disordered over two positions with occupancy factors of 0.808 (9):0.192 (9) and 0.922 (3):0.078 (3), respectively.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Vynohradov, OS; Pavlenko, VA; Naumova, DD; Partsevska, SV; Shova, S; Safarmamadov, SM or concate me.. Safety of 3,5-Dimethyl-1H-pyrazole

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Liu, CF; Liu, M; Dong, L in [Liu, Chen-Fei; Liu, Man; Dong, Lin] Sichuan Univ, West China Sch Pharm, Educ Minist, Key Lab Drug Targeting & Drug Delivery Syst, Chengdu 610041, Sichuan, Peoples R China published Iridium(III)-Catalyzed Tandem Annulation Synthesis of Pyrazolo[1,2-alpha]cinnolines from Pyrazolones and Sulfoxonium Ylides in 2019, Cited 55. SDS of cas: 86-92-0. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0.

A highly efficient iridium-catalyzed cascade annulation of pyrazolones and sulfoxonium ylides to access various pyrazolo[1,2-alpha]cinnoline derivatives has been achieved. This novel approach expanded the application scope of coupling partners to ylides. The control experiments were performed to give insight into the mechanism of this reaction.

SDS of cas: 86-92-0. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Liu, CF; Liu, M; Dong, L or concate me.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

An article Squaramide-catalyzed asymmetric Mannich reactions between 3-fluorooxindoles and pyrazolinone ketimines WOS:000477986000013 published article about CHIRAL SQUARAMIDE; MICHAEL ADDITION; DERIVATIVES; INHIBITORS; PYRAZOLIN-5-ONES; CONSTRUCTION; PYRAZOLONES in [Zhang, Qing-Da; Zhao, Bo-Liang; Li, Bing-Yu; Du, Da-Ming] Beijing Inst Technol, Sch Chem & Chem Engn, 5 South Zhongguancun St, Beijing 100081, Peoples R China in 2019, Cited 28. Recommanded Product: 86-92-0. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0

An enantioselective Mannich reaction between 3-fluorooxindoles and pyrazolinone ketimines has been developed for the construction of amino-pyrazolone-oxindoles containing stereogenic C-F units. Based on this new protocol that allows for the generation of two adjacent tetrasubstituted stereocenters, a variety of structurally diverse fluorinated amino-pyrazolone-oxindoles were obtained in good to excellent yields with excellent diastereoselectivities and enantioselectivities (up to 98% yield, >20 : 1 dr and >99% ee). What’s more, good yield and high stereoselectivities were obtained in the gram-scale reaction.

Recommanded Product: 86-92-0. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Zhang, QD; Zhao, BL; Li, BY; Du, DM or concate me.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Product Details of 67-51-6. In 2019.0 MOL CATAL published article about BRANCHED POLYETHYLENE; FUNCTIONALIZED POLYOLEFINS; ALKYLALUMINUM COCATALYST; METAL-COMPLEXES; NITROGEN DONOR; AMINE LIGANDS; POLYMERIZATION; ALUMINUM; NMR; TEMPERATURE in [Tuskaev, Vladislav A.; Zubkevich, Sergei V.; Gagieva, Svetlana Ch.; Bulychev, Boris M.] Moscow MV Lomonosov State Univ, Chem Dept, Leninskie Gory 11, Moscow 119991, Russia; [Tuskaev, Vladislav A.; Kononova, Elena G.; Khrustalev, Victor N.; Zarubin, Dmitry N.] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Vavilov Str 28, Moscow 119991, Russia; [Saracheno, Daniele] Dimitri Mendeleev Univ Chem Technol Russia, Higher Coll Chem Russia, Miusskaya Sq 9, Moscow 125047, Russia; [Dorovatovskii, Pavel V.; Khrustalev, Victor N.] Natl Res Ctr, Kurchatov Inst, Moscow, Russia; [Khrustalev, Victor N.] Peoples Friendship Univ Russia RUDN, Moscow, Russia; [Kissin, Yury V.] Rutgers State Univ, Dept Chem & Chem Biol, 123 Bevier Rd, Piscataway, NJ 08854 USA in 2019.0, Cited 73.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

Four new coordination compounds of nickel (II) with derivatives of N,N-bis(pyrazol-1-ylmethyl)propylamine were synthesized; their composition and structure were confirmed with IR-spectroscopy and elemental analysis. The structures of products 13 and 15 were unambiguously established in an X-ray diffraction study. Compounds 13 and 15 crystallize in the orthorhombic space groups Pna2(1) and P2(1)2(1)2(1) correspondingly and represent a monomeric octahedral nickel complexes, that are typical for tridentate scorpion-type ligands. New method for immobilization of nickel complexes with derivatives of N,N-bis(pyrazol-1-ylmethyl)propylamine on silica gel modified with aminopropyl groups was proposed. The EXAFS/XANES analysis indicated that Ni atom in the supported complexes adopt almost octahedral geometry, being partly surrounded by nitrogen atoms from organic ligand and partly grafted to silica surface through silanol groups, with Br- in outer coordination sphere. Both the original and the supported complexes, when activated with Et2AlCl or Et3Al2Cl3, catalyze ethylene oligomerization with the predominant formation of butene isomers. Generally, the immobilized complexes show higher activity and better selectivity towards 1-butene formation.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Tuskaev, VA; Zubkevich, SV; Saracheno, D; Gagieva, SC; Dorovatovskii, PV; Kononova, EG; Khrustalev, VN; Zarubin, DN; Bulychev, BM; Kissin, YV or concate me.. Product Details of 67-51-6

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Tuskaev, VA; Zubkevich, SV; Saracheno, D; Gagieva, SC; Dorovatovskii, PV; Kononova, EG; Khrustalev, VN; Zarubin, DN; Bulychev, BM; Kissin, YV in [Tuskaev, Vladislav A.; Zubkevich, Sergei V.; Gagieva, Svetlana Ch.; Bulychev, Boris M.] Moscow MV Lomonosov State Univ, Chem Dept, Leninskie Gory 11, Moscow 119991, Russia; [Tuskaev, Vladislav A.; Kononova, Elena G.; Khrustalev, Victor N.; Zarubin, Dmitry N.] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Vavilov Str 28, Moscow 119991, Russia; [Saracheno, Daniele] Dimitri Mendeleev Univ Chem Technol Russia, Higher Coll Chem Russia, Miusskaya Sq 9, Moscow 125047, Russia; [Dorovatovskii, Pavel V.; Khrustalev, Victor N.] Natl Res Ctr, Kurchatov Inst, Moscow, Russia; [Khrustalev, Victor N.] Peoples Friendship Univ Russia RUDN, Moscow, Russia; [Kissin, Yury V.] Rutgers State Univ, Dept Chem & Chem Biol, 123 Bevier Rd, Piscataway, NJ 08854 USA published Nickel(II) complexes with tripodal NNN ligands as homogenous and supported catalysts for ethylene oligomerization in 2019.0, Cited 73.0. Safety of 3,5-Dimethyl-1H-pyrazole. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

Four new coordination compounds of nickel (II) with derivatives of N,N-bis(pyrazol-1-ylmethyl)propylamine were synthesized; their composition and structure were confirmed with IR-spectroscopy and elemental analysis. The structures of products 13 and 15 were unambiguously established in an X-ray diffraction study. Compounds 13 and 15 crystallize in the orthorhombic space groups Pna2(1) and P2(1)2(1)2(1) correspondingly and represent a monomeric octahedral nickel complexes, that are typical for tridentate scorpion-type ligands. New method for immobilization of nickel complexes with derivatives of N,N-bis(pyrazol-1-ylmethyl)propylamine on silica gel modified with aminopropyl groups was proposed. The EXAFS/XANES analysis indicated that Ni atom in the supported complexes adopt almost octahedral geometry, being partly surrounded by nitrogen atoms from organic ligand and partly grafted to silica surface through silanol groups, with Br- in outer coordination sphere. Both the original and the supported complexes, when activated with Et2AlCl or Et3Al2Cl3, catalyze ethylene oligomerization with the predominant formation of butene isomers. Generally, the immobilized complexes show higher activity and better selectivity towards 1-butene formation.

Safety of 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Tuskaev, VA; Zubkevich, SV; Saracheno, D; Gagieva, SC; Dorovatovskii, PV; Kononova, EG; Khrustalev, VN; Zarubin, DN; Bulychev, BM; Kissin, YV or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Recently I am researching about CLINICAL-PRACTICE; SURVIVAL; MULTICENTER; ANTITUMOR; SAFETY; SITE; SEX, Saw an article supported by the BayerBayer AG; Amgen MerckAmgenMerck & Company; RocheRoche Holding. Published in DOVE MEDICAL PRESS LTD in ALBANY ,Authors: Novakova-Jiresova, A; Kopeckova, K; Boublikova, L; Chloupkov, R; Melichar, B; Petruzelka, L; Finek, J; Fiala, O; Grell, P; Batko, S; Linke, Z; Kiss, I; Prausov, J; Buchler, T. The CAS is 83-10-3. Through research, I have a further understanding and discovery of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Recommanded Product: 83-10-3

Purpose: Regorafenib is an oral multikinase inhibitor approved for the therapy of previously treated metastatic colorectal carcinoma (mCRC). The aim of the present study was to analyze the outcomes of treatment with regorafenib in real-world clinical practice based on data from a national registry. Methods: The CORECT registry, the Czech non-interventional database of patients with mCRC treated with targeted agents, searched for patients with metastatic CRC treated with regorafenib. In total, 555 evaluable patients were identified. Results: The median age at diagnosis was 61.7 years. All patients had disease progression on or after previous systemic treatment. Most patients were treated with an initial dose of 160 mg daily (n = 463; 83.6%). The median duration of treatment was 2.7 months (range 0.023.4 months). By the data cut-off date, 472 patients (85%) had completed treatment with regorafenib and were evaluable for treatment response evaluation. Partial response was reported in 13 patients (2.8%) and disease stabilization in 130 patients (27.5%). Median progression-free survival (PFS) and overall survival (OS) were 3.5 months (95% confidence interval [CI] 3.2-3.7 months) and 9.3 months (95% CI 8.3-10.3 months), respectively. The 6-month OS rate was 67.7% (95% CI 63.4-72.1%). Multivariable analysis showed that female gender, longer interval from diagnosis of metastatic disease, MO stage at diagnosis, and Eastern Cooperative Oncology Group performance status (ECOG PS) 0 were associated with longer PFS, while higher body-mass index (BMI), longer interval from diagnosis of metastatic disease, and ECOG PS of 0 were associated with longer OS. Conclusion: OS of patients treated with regorafenib in the real-world clinical practice in this cohort exceeded that reported in randomized trials. Regorafenib is a safe and active treatment option for a subgroup of patients with mCRC who are progressing after other systemic therapies and maintain good performance status.

Recommanded Product: 83-10-3. About 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid, If you have any questions, you can contact Novakova-Jiresova, A; Kopeckova, K; Boublikova, L; Chloupkov, R; Melichar, B; Petruzelka, L; Finek, J; Fiala, O; Grell, P; Batko, S; Linke, Z; Kiss, I; Prausov, J; Buchler, T or concate me.

Reference:
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Huang Daowei; Wang Wenya; Zhang Zhiguo; Jiang Ling; (45 pag.)CN107286140; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

An article Remote Charge Effects on the Oxygen-Atom-Transfer Reactivity and Their Relationship to Molybdenum Enzymes WOS:000458085900039 published article about ELECTRONIC-STRUCTURE CONTRIBUTIONS; SULFITE OXIDASE; ACTIVE-SITE; DIOXOMOLYBDENUM(VI) COMPLEXES; DIOXO-MO(VI) COMPLEX; DIOXYGEN ACTIVATION; CRYSTAL-STRUCTURE; CIS-DIOXO; LIGANDS; MODEL in [Paudel, Jaya; Li, Feifei] New Mexico State Univ, Dept Chem & Biochem, Las Cruces, NM 88003 USA; [Pokhrel, Amrit; Kirk, Martin L.] Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA in 2019.0, Cited 89.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. HPLC of Formula: C5H8N2

We report the syntheses, crystal structures, and characterization of the novel cis-dioxomolybdenum(VI) complexes [Tpm*(MoO2Cl)-O-VI](MoO2Cl3) (1) and [Tpm*(MoO2Cl)-O-VI](ClO4) (2), which are supported by the charge-neutral tris(3,5-dimethyl-1-pyrazolyl)methane (Tpm*) ligand. A comparison between isostructural [Tpm*(MoO2Cl)-O-VI](+) and Tp*(MoO2Cl)-O-VI [Tp* = hydrotris(3,5-dimethyl-1-pyrazolyl)borate] reveals the effects of one unit of overall charge difference on their spectroscopic and electrochemical properties, geometric and electronic structures, and O-atom-transfer (OAT) reactivities, providing new insight into pyranopterin molybdoenzyme OAT reactivity. Computational studies of these molecules indicate that the delocalized positive charge lowers the lowest unoccupied molecular orbital (LUMO) energy of cationic [Tpm*MoO2Cl](+) relative to Tp*MoO2Cl. Despite their virtually identical geometric structures revealed by crystal structures, the Mo-VI/Mo-V redox potential of 2 is increased by 350 mV relative to that of Tp*(MoO2Cl)-O-VI. This LUMO stabilization also contributes to an increased effective electrophilicity of [Tp*MoO2Cl](+) relative to that of Tp*MoO2Cl, resulting in a more favorable resonant interaction between the molydenum complex LUMO and the highest occupied molecular orbital (HOMO) of the PPh3 substrate. This leads to a greater thermodynamic driving force, an earlier transition state, and a lowered activation barrier for the orbitally controlled first step of the OAT reaction in the Tpm* system relative to the Tp* system. An Eyring plot analysis shows that this initial step yields an O Mo-IV-OPPh3 intermediate via an associative transition state, and the reaction is similar to 500-fold faster for 2 than for Tp*MoO2Cl. The second step of the OAT reaction entails solvolysis of the O Mo-IV-OPPh3 intermediate to afford the solvent-substituted Mo-IV product and is 750-fold faster for the Tpm* system at -15 degrees C compared to the Tp* system. The observed rate enhancement for the second step is ascribed to a switch of the reaction mechanism from a dissociative pathway for the Tp* system to an alternative associative pathway for the Tpm* system. This is due to a more Lewis acidic Mo-IV center in the Tpm* system.

HPLC of Formula: C5H8N2. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Paudel, J; Pokhrel, A; Kirk, ML; Li, FF or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

COA of Formula: C12H12N2O3. Recently I am researching about DECORRELATION; SPECKLE; TISSUE, Saw an article supported by the Pazmany Peter Catholic University [KAP14-17]; Janos Bolyai scholarship of the Hungarian Academy of Sciences of the Hungarian National Research, Development and Innovation Office – NKFIH [PD 121105, EFOP-3.6.3-VEKOP-16-2017-00002, GINOP-2.1.7-15-2016-02201]. Published in ELSEVIER SCIENCE BV in AMSTERDAM ,Authors: Csany, G; Szalai, K; Gyongy, M. The CAS is 83-10-3. Through research, I have a further understanding and discovery of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid

The current work investigates the performance of a real-time scan conversion algorithm for generating a 2-D ultrasound image from a laterally scanned single-element ultrasound transducer, which has applications in point-of-care devices such as for skin imaging. The algorithm employs a fixed calibration curve to update a predefined image grid in real time. Simulations showed that the calibration curve (with a maximum of 1) is robust to changes in scatterer concentration (8.3 x 10(-3) mean absolute error), signal to noise ratio (1.0 x 10(-3) mean absolute error for -5 dB SNR), and can be accurately predicted from a small number (31) of point scatterers (6.9 x 10(-3) mean absolute error). Good agreement was also found between the calibration curves obtained from simulated and experimental data (1.19 x 10(-2) mean absolute error). The scan conversion algorithm was validated by evaluation of the position estimation errors on both simulations and experiments. Clinical images of skin lesions (N = 20) demonstrate the feasibility of the algorithm for real, non-homogeneous tissue. Use of a fixed calibration curve compared to an adaptive calibration curve gave similar accuracies in the scanning step size range of 150-350 mu m (with an average overlap of the accuracy ranges of 92.94% for simulations and 42.83% for experiments), and a 350-fold improvement in computation time.

COA of Formula: C12H12N2O3. About 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid, If you have any questions, you can contact Csany, G; Szalai, K; Gyongy, M or concate me.

Reference:
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Huang Daowei; Wang Wenya; Zhang Zhiguo; Jiang Ling; (45 pag.)CN107286140; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

An article Synthesis of pyrazolones and pyrazoles via Pd-catalyzed aerobic oxidative dehydrogenation WOS:000466245000011 published article about AGENTS; DERIVATIVES in [Zhu, Ye-Fu; Wei, Bo-Le; Wei, Jiao-Jiao; Wang, Wen-Qiong; Song, Wei-Bin; Xuan, Li-Jiang] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China; [Zhu, Ye-Fu; Wei, Bo-Le; Wei, Jiao-Jiao] Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China in 2019, Cited 18. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0. Formula: C11H12N2O

A palladium-catalyzed oxidative dehydrogenation reaction in the presence of AMS and base to synthesize pyrazolones and pyrazoles was identified. This method can be utilized to a wide range of substrates, operates under mild react conditions and can give high yields. We believe it could be used as an alternative protocol for the classical dehydrogenation reactions. (C) 2019 Published by Elsevier Ltd.

Formula: C11H12N2O. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Zhu, YF; Wei, BL; Wei, JJ; Wang, WQ; Song, WB; Xuan, LJ or concate me.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics