Category: 14580-22-4

Pandit, Rameshwar Prasad published the artcileEfficient one-pot synthesis of novel and diverse tetrahydroquinolines bearing pyranopyrazoles using organocatalyzed domino Knoevenagel/hetero Diels-Alder reactions, Formula: C10H9ClN2O, the publication is Molecular Diversity (2014), 18(1), 39-50, database is CAplus and MEDLINE.

A new synthetic route to biol. interesting diverse tetrahydroquinoline derivatives bearing pyranopyrazole groups was developed and the synthesis of the target compounds was achieved by a reaction of pyrazolones and N,N-dialkylated aminobenzaldehyde derivatives in the presence of 1,2-Ethanediamine acetate (1:2) (EDDA, ethylenediammonium diacetate). The key strategy underlying the methodol. used was the domino Knoevenagel/hetero Diels-Alder reaction. This synthetic method provides a variety of novel tetrahydroquinolines in good yields. The title compounds thus formed included a heterocyclic compound (I) and related substances. The synthesis of the target compounds was achieved by a reaction of 2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one derivatives with 2-[methyl(3-methyl-2-buten-1-yl)amino]benzaldehyde (prenylamine derivative), 2-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]methylamino]benzaldehyde (trans-geranylamine derivative), 2-[methyl[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]amino]benzaldehyde (trans,trans-farnesylamine derivative).

Molecular Diversity published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Formula: C10H9ClN2O.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parmar, Narsidas J. published the artcileAn efficient domino Knoevenagel/hetero-Diels-Alder route to some novel thiochromenoquinoline-fused polyheterocycles, Computed Properties of 14580-22-4, the publication is Monatshefte fuer Chemie (2014), 145(7), 1179-1189, database is CAplus.

The 2-alkenylthiopyranoquinoline-3-carbaldehyde derived from 2-mercaptoquinoline-3-carbaldehyde and citral underwent smooth domino Knoevenagel/hetero-Diels-Alder reaction with heterocyclic mono- or diketones in tetrabutylammonium hydrogensulfate under solvent-free conditions and afforded a new class of thiochromenoquinoline-fused heterocycles in good yields. The reaction is highly diastereoselective and can be applied to analogs of carbocyclic diketones as well. The stereochem. of the products was confirmed by single-crystal X-ray diffraction and 2D NMR NOESY data.

Monatshefte fuer Chemie published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Computed Properties of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Hoeppner, F. D. published the artcileMO calculations on photographic development. IX. Experimental and quantum chemical investigations on the acidity of 5-pyrazolones, Computed Properties of 14580-22-4, the publication is Journal fuer Praktische Chemie (Leipzig) (1976), 318(4), 555-64, database is CAplus.

The pKs values of 49 derivatives of 5-pyrazolone were measured by potentiometric titration and their 1H-NMR spectra were recorded in Me2SO-d6. The exptl. acidity order correlates with both Hammett substitution constants and HMO electron densities.

Journal fuer Praktische Chemie (Leipzig) published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Computed Properties of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Purohit, Vishal B. published the artcilePalladium N-heterocyclic carbene catalyzed regioselective C-H halogenation of 1-aryl-3-methyl-1H-pyrazol-5(4H)-ones using N-halosuccinimides (NXS), Quality Control of 14580-22-4, the publication is Catalysis Science & Technology (2015), 5(6), 3113-3118, database is CAplus.

A novel palladium N-heterocyclic carbene [Pd(NHC)Cl₂] complex of vitamin B₁ was synthesized and characterized by ¹H NMR, EDX, FT-IR and UV-visible spectroscopy. The complex was used as a catalyst for regioselective ortho-C-H chlorination/bromination of 1-aryl-3-methyl-1H-pyrazol-5(4H)-ones via C-H bond activation utilizing Ag₂O as the effective terminal additive. The catalyst was easy to prepare, efficient and found to be highly regioselective, affording the target products in moderate to excellent yields.

Catalysis Science & Technology published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Quality Control of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Zhu, Song-Lei published the artcileA simple and efficient one-pot synthesis of spirooxindoles in water under microwave irradiation conditions, HPLC of Formula: 14580-22-4, the publication is Letters in Organic Chemistry (2008), 5(4), 319-323, database is CAplus.

A simple and efficient method for the synthesis of spirooxindoles derivatives by one-pot reactions of isatins, activated methylene reagents, and activated carbonyl compounds in water under microwave irradiation was reported. This protocol has the advantages of short reaction time, high yields, easy work-up procedure, and environmentally benign characters.

Letters in Organic Chemistry published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C7H8FNO2S, HPLC of Formula: 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Patel, N. C. published the artcileSynthesis of bisazo disperse dyes based on 4-hydroxyl-1-phenylquinolin-2(1H)-one system and their dyeing performance on polyester fabric, Application In Synthesis of 14580-22-4, the publication is Journal of Indian Council of Chemists (2001), 18(1), 59-62, database is CAplus.

Ten 3-[4-(arylazo)phenylazo]-4-hydroxy-1-phenyl-2(1H)-quinolinone dyes were prepared by coupling diazotized 3-(4-aminophenylazo)-4-hydroxy-1-phenyl-2(1H)-quinolinone with various coupling components. 4-Hydroxy-1-phenyl-2(1H)-quinolinone (I) was prepared by the condensation of o-chlorobenzoic acid and aniline giving N-phenylanthranilic acid followed by acetylation giving N-acetyl-N-phenylanthranilic acid and ring closure. I was coupled with diazotized 4-aminoacetanilide giving a monoazo compound which on hydrolysis gave the diazo component for disazo dye preparation The dyes were characterized by elemental and spectral analyses and their dyeing performance on polyester fabric was assessed. The dyes when applied on polyester fabric gave shades with poor to good light fastness, very good to excellent wash fastness, and poor to excellent exhaustion.

Journal of Indian Council of Chemists published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Application In Synthesis of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Patel, N. C. published the artcileSynthesis and application of some bisazo disperse dyes based on 4-hydroxyquinolinoquinazoline system on polyester fabric, Name: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is Journal of Indian Council of Chemists (2001), 18(2), 83-86, database is CAplus.

Ten 3-(4′-R-azo-1′-phenylazo)-4-hydroxyquinolino-[1,2-b]-4-oxoquinazolines were prepared by coupling diazotized 3-(4′-amino-1′-phenylazo)-4-hydroxyquinolino-[1,2-b]-4-oxoquinazoline with various coupling components. 4-Hydroxyquinolino-[1,2-b]-4-oxoquinazoline (I) was prepared by the condensation of 2-methyl-1,3-benzoxazin-8-one with anthranilic acid, giving initially 2-methyl-3-(1-carboxyphenyl)-4-oxoquinazoline followed by the ring closure. I was coupled with diazotized p-aminoacetanilide followed by hydrolysis to give 3-[4′-amino-1′-phenylazo]-4-hydroxyqinolino[1,2-b]-4-oxoquinazoline. The bisazo disperse dyes were characterized by elemental and spectral analyses and their dyeing performance on polyester fabric was assessed. These compounds when applied on polyester fabric, gave shades with poor to good light fastness, very good to excellent wash fastness and poor to excellent exhaustion.

Journal of Indian Council of Chemists published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Name: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parekh, Nikhil M. published the artcileSynthesis of heterocyclic monoazo dyes derived from 1H-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine: their antimicrobial activity and their dyeing performance on various fibers, Application In Synthesis of 14580-22-4, the publication is Research on Chemical Intermediates (2012), 38(3-5), 885-901, database is CAplus.

Heterocyclic monoazobenzoquinoline-based azo dyes have been derived by diazotization of 1H-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine with a variety of phenylpyrazolone-based coupling compounds The synthesized dyes were characterized by determination of their percentage yield, by elemental anal., and by UV-visible, IR, and ¹H NMR spectroscopy. Dyeing performance on silk, wool, nylon, and polyester fibers was assessed. The fastness properties of the dyes on each fiber were moderate to excellent. The antimicrobial activity of the dyes at different concentrations were also examined, by use of the Kirby-Bauer disk diffusion method.

Research on Chemical Intermediates published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Application In Synthesis of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parekh, Nikhil M. published the artcileColorimetric studies of heterocyclic monoazo dyes on various fibres, Recommanded Product: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is Indian Journal of Fibre & Textile Research (2012), 37(4), 372-377, database is CAplus.

A series of heterocyclic monoazo quinazolinone based heterocyclic monoazo dyes derived by the diazotization of 3-(4-aminophenyl)-2-phenylquinazolin-4(3H)-one with various Ph pyrazolones based coupling components has been studied. These dyes give mostly yellow shades. All the heterocyclic monoazo dyes have been characterized by their % yield, UV-VIS spectroscopy, IR spectroscopy, ¹H NMR spectroscopy, and dyeing performance on silk, wool, nylon, and polyester fibers. The percentage dye bath exhaustion on different fibers is found to be reasonably good and acceptable. The dyed fibers show moderate to very good light fastness and good to excellent washing and rub fastness properties. Spectral properties and colorimetric data (L*, a*, b*, C*, H*, K/S) have also been investigated.

Indian Journal of Fibre & Textile Research published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Recommanded Product: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parekh, Nikhil M. published the artcileAntituberculosis and antibacterial evaluations of some novel phenyl pyrazolone-substituted 1H-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine derivatives, Product Details of C10H9ClN2O, the publication is Medicinal Chemistry Research (2012), 21(12), 4168-4176, database is CAplus.

Coupling of various phenylpyrazolone derivatives with diazonium salt of 1H-benzo[g]pyrazolo[3,4-b]quinolin-3-ylamine gave a series of heterocyclic azo compounds All the synthesized azo compounds have been characterized by their percentage yield, elemental, and spectral analyses. These new compounds were evaluated for their in vitro antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa. Furthermore, the synthesized compounds were tested for in vitro antituberculosis activity against Mycobacterium tuberculosis. Streptomycin, Isoniazid, Rifampicin, and Ethambutol were used as standards in this investigation.

Medicinal Chemistry Research published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Product Details of C10H9ClN2O.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics