Synthetic Route of 20157-44-2, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 20157-44-2 as follows.
To a 10 mL sealed tube was placed substrate 1j (47.5 mg, 0.3 mmol, 1.0 equiv), and then the tube wasevacuated and backfilled with argon (x3). To the reaction tube were added 0.15 mL of toluene (2.0 M),norbornene (141.2 mg, 1.5 mmol, 5.0 equiv), RuH2(CO)(PPh3)3 (2.8 mg, 0.003 mmol, 1 mol%), andHSiEt3 (174.4 mg, 0.24 mL, 1.5 mmol, 5.0 equiv). The system was closed and stirred at 100 C for 20 h.After removal of the solvent under reduced pressure, the yield of arylsilane 2j was determined by 1HNMR analysis using 1,1,2,2-tetrachloroethane as an internal standard.
According to the analysis of related databases, 20157-44-2, the application of this compound in the production field has become more and more popular.
Reference:
Article; Mita, Tsuyoshi; Tanaka, Hiroyuki; Michigami, Kenichi; Sato, Yoshihiro; Synlett; vol. 25; 9; (2014); p. 1291 – 1294;,
Pyrazole – Wikipedia,
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