Analyzing the synthesis route of 3,5-Dibromo-4-nitro-1H-pyrazole

According to the analysis of related databases, 104599-36-2, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 104599-36-2, name is 3,5-Dibromo-4-nitro-1H-pyrazole, This compound has unique chemical properties. The synthetic route is as follows., Formula: C3HBr2N3O2

0.369 mol of sodium acetate was introduced into a solution of 0.184 mol of dibromonitropyrazole in 250 ml of N-methylpyrrolidone in a 500 ml three-necked flask, and the reaction medium was brought to 80 C. 0.369 mol of 3-bromopropanol was added dropwise at this temperature. This temperature was maintained for 5 hours. After cooling to room temperature, the medium was poured onto ice with stirring. The 3-(3,5-dibromo-4-nitro-1H-pyrazol-1-yl)propan-1-ol (compound 1) precipitated. It was filtered off by suction, dried, and obtained in a yield of 75%. The mass of the expected compound C6H7Br2N3O3 was detected by mass spectrometry. The NMR analyses (1H 400 MHz and 13C 100.61 MHz DMSO d6) were in accordance with the expected structure.

According to the analysis of related databases, 104599-36-2, the application of this compound in the production field has become more and more popular.