Category: 67-51-6

I found the field of Crystallography very interesting. Saw the article Crystal structure of dichlorido-1 kappa Cl,2 kappa Cl-(mu(2)-3,5-dimethyl-1H-pyrazolato-1 kappa N-2:2 kappa N-1)(3,5-dimethyl-1H-pyrazole-2 kappa N-2){mu-2-[(2-hydroxyethyl)amino-1 kappa N-2,O]ethanolato-1:2 kappa O-2:O}dicopper(II) published in 2020.0. SDS of cas: 67-51-6, Reprint Addresses Safarmamadov, SM (corresponding author), Tajik Natl Univ, Dept Chem, 17 Rudaki Ave, Dushanbe 734025, Tajikistan.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

The title compound, [Cu-2(C5H7N2)(C4H10NO2)Cl-2(C5H8N2)], is a pyrazolate aminoalcohol complex which contains two dimethylpyrazole molecules in monodentate and bidentate-bridged coordination modes and a monodeprotonated diethanolamine molecule. Both copper atoms are involved in the formation of non-planar five-membered chelate rings. One Cu atom is in a distorted tetrahedral environment formed by the pyridine nitrogen atom of the protonated dimethylpyrazole molecule, the N atom of the deprotonated bridged dimethylpyrazole, the Cl atom and the bridged O atom of the monodeprotonated diethanolamine. The second Cu atom has an intermediate environment between trigonal bipyramidal and square pyramidal, formed by the N atom of the deprotonated bridged dimethylpyrazole, the Cl atom and the N atom of the aminoalcohol, and two O atoms of the deprotonated and protonated OH groups. In the crystal, N-H center dot center dot center dot Cl hydrogen bonds link the molecules into antisymmetric chains running along the a-axis direction. Adjacent chains are connected by O-H center dot center dot center dot O hydrogen bonds involving the hydroxyl group as donor.

SDS of cas: 67-51-6. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Vynohradov, OS; Pavlenko, VA; Safyanova, IS; Znovjyak, K; Shova, S; Safarmamadov, SM or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Electrochemical oxidative C-H/N-H cross-coupling for C-N bond formation with hydrogen evolution published in 2019.0. Computed Properties of C5H8N2, Reprint Addresses Lei, AW (corresponding author), Jiangxi Normal Univ, Natl Res Ctr Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China.; Lei, AW (corresponding author), Wuhan Univ, IAS, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

Under metal catalyst-free and exogenous-oxidant-free conditions, a series of C-3 aminated imidazo[1,2-a]pyridines were synthesized by electrochemical intermolecular oxidative C-H/N-H cross-coupling. Furthermore, by using a catalytic amount of ferrocene as the mediator, electrochemical intramolecular oxidative C-H/N-H cross-coupling for the synthesis of 10H-benzo[4,5] imidazo[1,2-a]indole derivatives has also been accomplished.

Computed Properties of C5H8N2. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Yu, Y; Yuan, Y; Liu, HL; He, M; Yang, MZ; Liu, P; Yu, BY; Dong, XC; Lei, AW or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Merging photoredox catalysis with transition metal catalysis: Direct C4-H amination of 8-hydroxyquinoline derivatives published in 2019. Product Details of 67-51-6, Reprint Addresses Yang, F; Wu, YJ (corresponding author), Zhengzhou Univ, Key Lab Appl Chem Henan Univ, Henan Key Lab Chem Biol & Organ, Coll Chem & Mol Engn, Zhengzhou 450052, Henan, Peoples R China.; Wu, YS (corresponding author), TetranovBiophann LLC, Zhengzhou 450001, Henan, Peoples R China.; Wu, YS (corresponding author), Collaborat Innovat Ctr New Drug Res & Safety Eval, Zhengzhou 450001, Henan, Peoples R China.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

A practical and efficient protocol for Ag/Ru-cocatalyzed regioselective C-H amination of 8-hydroxyquinoline esters with pyrazoles was developed, This reaction proceeded smoothly via a photoredox-mediated direct C-H/N-H oxidative coupling process. The remarkable features of this reaction include the wide substrate scope, mild reaction conditions and high regioselectivity at the C4 site of the quinolinyl moiety. (C) 2019 Elsevier Ltd. All rights reserved.

Product Details of 67-51-6. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Ma, YY; Shi, YQ; Yang, F; Wu, YS; Wu, YJ or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Switching the site-selectivity of C-H activation in aryl sulfonamides containing strongly coordinating N-heterocycles published in 2019.0. Safety of 3,5-Dimethyl-1H-pyrazole, Reprint Addresses Xu, H (corresponding author), Chinese Acad Med Sci, Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China.; Xu, H (corresponding author), Chinese Acad Med Sci, Peking Union Med Coll, Inst Mat Med, Beijing Key Lab Act Subst Discovery & Druggabil E, Beijing 100050, Peoples R China.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

The limitations of arene C-H functionalization of aryl sulfonamides containing strongly coordinating Nheterocycles were overcome using a Rh(III) catalyst. The site-selectivity of C-H carbenoid functionalization at the ortho position relative to either the sulfonamide or N-heterocycle directing groups was elegantly switched using solvents of different polarities and different additive concentrations. Importantly, sulfonamide-group-directed ortho-C-H carbenoid functionalization tolerated strongly coordinating N-heterocycles, including pyridine, pyrrole, thiazole, pyrimidine, and pyrazine. Density functional theory (DFT) calculations were performed to rationalize the reaction mechanisms and the influence of reaction polarity.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Dong, Y; Zhang, XP; Chen, JJ; Zou, WX; Lin, SW; Xu, H or concate me.. Category: pyrazoles-derivatives

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Quality Control of 3,5-Dimethyl-1H-pyrazole. I found the field of Chemistry very interesting. Saw the article Lithium Chloride Catalyzed Aza-Michael Addition of Pyrazoles to alpha,beta-Unsaturated Imides published in 2019.0, Reprint Addresses Zhou, HY (corresponding author), Gansu Agr Univ, Coll Sci, Lanzhou 730070, Peoples R China.; Zhou, HY; Yang, JY (corresponding author), Northwest Normal Univ, Coll Chem & Chem Engn, Lanzhou 730070, Peoples R China.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole.

A lithium chloride catalyzed aza-Michael reaction of pyrazoles to alpha,beta-unsaturated imides has been developed. A range of aromatic and aliphatic alpha,beta-unsaturated imides are found to be suitable for the established method, providing the corresponding aza-Michael adducts in up to 93% yields. The inexpensive catalyst, good substrate tolerance, and ease of scale-up make this procedure highly practical.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Zhou, HY; Xiang, XC; Ma, B; Wang, GG; Zhang, ZX; Yang, JY or concate me.. Recommanded Product: 67-51-6

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Safety of 3,5-Dimethyl-1H-pyrazole. I found the field of Chemistry; Science & Technology – Other Topics; Engineering very interesting. Saw the article Performance of Base and Noble Metals for Electrocatalytic Hydrogenation of Bio-Oil-Derived Oxygenated Compounds published in 2020.0, Reprint Addresses Gutierrez, OY; Holladay, JD (corresponding author), Pacific Northwest Natl Lab, Inst Integrated Catalysis, Energy & Environm Directorate, Richland, WA 99352 USA.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole.

Electrocatalytic hydrogenation is a particularly attractive approach for converting the most unstable compounds in biogenic feedstocks at ambient conditions without external H-2. Here, we synthesized a variety of carbon-supported transition metal catalysts and characterized their activity for the electrocatalytic hydrogenation of a series of model compounds and pyrolysis bio-oil. Carbonyl compounds, especially aromatic aldehydes, such as furfural and benzaldehyde, are particularly inclined to hydrogenation driven by an applied current. This was verified with pure solutions of the model compounds and with pyrolysis bio-oil, where we achieved stable and steady continuous operation on Pd. When optimal catalyst composition was chosen, the conversion of benzaldehyde shifted from alcohol production (e.g., on Pd and Cu) to dimerization (e.g., on Co, Ni, and Zn). Pd and Cu were shown to offer the best compromise between reaction rates and efficiency although, in general, base metals offer similar conversions but better efficiencies than noble metals. Thus, the present work offers foundational results and guidelines for choosing the optimal metal catalyst and the applied potential for processing organic feedstocks as a function of its composition.

Safety of 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Andrews, E; Lopez-Ruiz, JA; Egbert, JD; Koh, K; Sanyal, U; Song, M; Li, DS; Karkamkar, AJ; Derewinski, MA; Holladay, J; Gutierrez, OY; Holladay, JD or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Switching the site-selectivity of C-H activation in aryl sulfonamides containing strongly coordinating N-heterocycles WOS:000488472900018 published article about LATE-STAGE FUNCTIONALIZATION; DIAZO-COMPOUNDS; RH(III)-CATALYZED SYNTHESIS; BOND FUNCTIONALIZATION; DIRECT ARYLATION; CROSS-COUPLINGS; ACCESS; OLEFINATION; OXIDES; CYCLIZATION in [Dong, Yi; Chen, Jiajing; Zou, Wenxing; Lin, Songwen; Xu, Heng] Chinese Acad Med Sci, Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China; [Dong, Yi; Chen, Jiajing; Zou, Wenxing; Lin, Songwen; Xu, Heng] Chinese Acad Med Sci, Peking Union Med Coll, Inst Mat Med, Beijing Key Lab Act Subst Discovery & Druggabil E, Beijing 100050, Peoples R China; [Zhang, XuePeng] Peking Univ, Shenzhen Grad Sch, Lab Computat & Drug Design, Shenzhen 518055, Peoples R China in 2019.0, Cited 93.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole

The limitations of arene C-H functionalization of aryl sulfonamides containing strongly coordinating Nheterocycles were overcome using a Rh(III) catalyst. The site-selectivity of C-H carbenoid functionalization at the ortho position relative to either the sulfonamide or N-heterocycle directing groups was elegantly switched using solvents of different polarities and different additive concentrations. Importantly, sulfonamide-group-directed ortho-C-H carbenoid functionalization tolerated strongly coordinating N-heterocycles, including pyridine, pyrrole, thiazole, pyrimidine, and pyrazine. Density functional theory (DFT) calculations were performed to rationalize the reaction mechanisms and the influence of reaction polarity.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Dong, Y; Zhang, XP; Chen, JJ; Zou, WX; Lin, SW; Xu, H or concate me.. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Robinson, H; Oatley, SA; Rowedder, JE; Slade, P; Macdonald, SJF; Argent, SP; Hirst, JD; McInally, T; Moody, CJ in [Robinson, Henry; McInally, Thomas] Univ Nottingham, Sch Chem, GSK Carbon Neutral Labs Sustainable Chem, Jubilee Campus,Triumph Rd, Nottingham NG7 2TU, England; [Oatley, Steven A.; Argent, Stephen P.; Hirst, Jonathan D.; Moody, Christopher J.] Univ Nottingham, Sch Chem, Univ Pk, Nottingham NG7 2RD, England; [Rowedder, James E.; Slade, Pawel; Macdonald, Simon J. F.] GlaxoSmithKline Med Res Ctr, Med Sci & Technol, Gunnels Wood Rd, Stevenage SG1 2NY, Herts, England published Late-Stage Functionalization by Chan-Lam Amination: Rapid Access to Potent and Selective Integrin Inhibitors in 2020.0, Cited 39.0. Product Details of 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

A late-stage functionalization of the aromatic ring in amino acid derivatives is described. The key step is a copper-catalysed diversification of a boronate ester by amination (Chan-Lam reaction) that can be carried out on a complex beta-aryl-beta-amino acid scaffold. This not only considerably extends the substrate scope of amination partners, but also delivers an array of potent and selective integrin inhibitors as potential treatment agents of idiopathic pulmonary fibrosis (IPF). This versatile chemical strategy, which is amenable to high-throughput-array protocols, allows the installation of pharmaceutically valuable heteroaromatic fragments at a late stage by direct coupling to NH heterocycles, leading to compounds with drug-like attributes. It thus constitutes a useful addition to the medicinal chemist’s repertoire.

Product Details of 67-51-6. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Robinson, H; Oatley, SA; Rowedder, JE; Slade, P; Macdonald, SJF; Argent, SP; Hirst, JD; McInally, T; Moody, CJ or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Fast and Efficient Nickel(II)-catalysed Transfer Hydrogenation of Quinolines with Ammonia Borane WOS:000584604700001 published article about CATALYZED TRANSFER HYDROGENATION; ASYMMETRIC HYDROGENATION; SODIUM-BOROHYDRIDE; MILD; DEHYDROGENATION; SEMIHYDROGENATION; REACTIVITY; ALKYNES; HETEROCYCLES; ALKYLATION in [Vermaak, Vincent; Vosloo, Hermanus C. M.; Swarts, Andrew J.] North West Univ, Res Focus Area Chem Resource Beneficiat, Catalysis & Synth Res Grp, 11 Hofmann St, ZA-2520 Potchefstroom, South Africa in 2020.0, Cited 42.0. Category: pyrazoles-derivatives. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

Herein we report the first Ni(II)-catalysed transfer hydrogenation of quinolines using ammonia borane (AB) as hydrogen (H-2) source. An in situ generated Ni(II)-bis(pyrazolyl)pyridine pre-catalyst could hydrogenate quinoline and its derivatives in excellent yields of up to 90% at 25 degrees C in 30 minutes. Spectroscopic studies revealed that a Ni(II)-hydride is responsible for the transfer hydrogenation of quinoline to 1,2,3,4-tetrahydroquinoline via a 1,4-dihydroquinoline intermediate.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Vermaak, V; Vosloo, HCM; Swarts, AJ or concate me.. Product Details of 67-51-6

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Zulu, S; Alam, MG; Ojwach, SO; Akerman, MP in [Zulu, Siyabonga; Alam, Mohd. G.; Ojwach, Stephen O.; Akerman, Matthew P.] Univ KwaZulu Natal, Sch Chem & Phys, Pietermaritzburg Campus,Private Bag X01, ZA-3209 Scottsville, South Africa; [Alam, Mohd. G.] Addis Ababa Sci & Technol Univ, Dept Ind Chem, POB 16417, Addis Ababa, Ethiopia published Structural and theoretical studies of the methoxycarbonylation of higher olefins catalysed by (Pyrazolyl-ethyl)pyridine palladium (II) complexes in 2019.0, Cited 51.0. Recommanded Product: 3,5-Dimethyl-1H-pyrazole. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

Reactions of 2-[1-(3,5-dimethylpyrazol-1-yl)ethyl]pyridine (L1) and 2-[1-(3,5-diphenylpyrazol-1-yl)ethyl]pyridine (L2) with the [Pd (COD)Cl-2] or [Pd (COD)MeCl] produced palladium (II) complexes [Pd(L1)ClMe] (1), [Pd(L1)Cl-2] (C2), [Pd(L2)ClMe] (3), and [Pd(L2)Cl-2] (4) in quantitative yields. Solid state structures of complexes 1, 3 and 4 established the formation of mononuclear compounds, containing one bidentate ligand unit per metal atom, to give square planar complexes. All the other spectroscopic characterization data and elemental analyses were consistent with the observed structures. All the palladium (II) complexes 1-4 gave active catalysts in the methoxycarbonylation of 1-octenes. The catalysts demonstrated 100% chemoselectivities towards esters and favored the formation of linear isomers. Reaction conditions such as the type of phosphine derivative, acid promoter, solvent system, time, pressure and temperature have been investigated and shown to affect both the catalytic activity and regio-selectivity of the catalysts. Solid-angle modelling established the comparable steric contributions from the ligands, consistent with the similar regioselectivities of the resultant catalysts.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Zulu, S; Alam, MG; Ojwach, SO; Akerman, MP or concate me.. SDS of cas: 67-51-6

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics